Propofol: Risk vs. Benefit

Laham, J

doi:10.1177/000992280204100103

Cited by 6 publications

(1 citation statement)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hypertriglyceridemia may appear after high-rate infusions; clinicians should also be aware of the propofol infusion syndrome (PRIS) to detect it as soon as possible. PRIS manifests as metabolic acidosis, hyperkalemia, rhabdomyolysis, hypoxia and progressive myocardial failure [7][8][9].…”

Section: Propofolmentioning

confidence: 99%

Sedation in TBI Patients

Peluso¹,

López²,

Badenes³

2019

Traumatic Brain Injury - Neurobiology, Diagnosis and Treatment

View full text Add to dashboard Cite

Sedation is an important topic in neurocritical patients. When compared with general intensive care unit and traumatic brain-injured patients, sedation has its therapeutic indications, such as management of intracranial pressure, treatment of status epilepticus, sedation for targeted temperature management patients and paroxysmal sympathetic activity. Nowadays, the assessment of sedation is done by neurological evaluation and new monitors based on electroencephalography signals that help the physician titrate the sedative agents. Therefore, the aim of this chapter is to discuss the main pharmacological properties of sedatives and analgesics, their proper indications related to pathophysiological issues and their titrations based on the abovementioned new technologies.

show abstract

Section: Propofolmentioning

confidence: 99%

Sedation in TBI Patients

Peluso¹,

López²,

Badenes³

2019

Traumatic Brain Injury - Neurobiology, Diagnosis and Treatment

View full text Add to dashboard Cite

show abstract

Sedation and Analgesia in Neurointensive Care

Villa

Citerio

2013

Textbook of Neurointensive Care

View full text Add to dashboard Cite

Estimation of effective dose and lifetime attributable risk from multiple head CT scans in ventriculoperitoneal shunted children

Aw-Zoretic

Seth

Katzman

et al. 2014

European Journal of Radiology

View full text Add to dashboard Cite

Purpose The purpose of this review is to determine the averaged effective dose and lifetime attributable risk factor from multiple head computed tomography (CT) dose data on children with ventriculoperitoneal shunts (VPS). Method and materials A total of 422 paediatric head CT exams were found between October 2008 and January 2011 and retrospectively reviewed. The CT dose data was weighted with the latest IRCP 103 conversion factor to obtain the effective dose per study and the averaged effective dose was calculated. Estimates of the lifetime attributable risk were also calculated from the averaged effective dose using a conversion factor from the latest BEIR VII report. Results Our study found the highest effective doses in neonates and the lowest effective doses were observed in the 10–18 years age group. We estimated a 0.007% potential increase risk in neonates and 0.001% potential increased risk in teenagers over the base risk. Conclusion Multiple head CTs in children equates to a slight potential increase risk in lifetime attributable risk over the baseline risk for cancer, slightly higher in neonates relative to teenagers. The potential risks versus clinical benefit must be assessed.

show abstract

Propofol: Risk vs. Benefit

Cited by 6 publications

References 18 publications

Sedation in TBI Patients

Sedation in TBI Patients

Sedation and Analgesia in Neurointensive Care

Estimation of effective dose and lifetime attributable risk from multiple head CT scans in ventriculoperitoneal shunted children

Contact Info

Product

Resources

About