Propolis: Effect of different concentrations, extracts and intake period on seric biochemical variables

Mani, Fernanda; Damasceno, Hélide C. R.; Novelli, Ethel L. B.; Martins, Edson Aparecido; Sforcin, José Maurício

doi:10.1016/j.jep.2005.10.011

Cited by 99 publications

(52 citation statements)

References 25 publications

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“…It is likely that flavonoids are the active ingredients in propolis, considering the pharmacological roles of these compounds. Esters of cinnamic and cafferic acids are among the flavonoids in propolis that have been found to play various physiological and pharmacological roles (Miyataka et al 1997;Burdock 1998;Lee et al 2005) such as anticancer, antibacteria, antivirus, antibiotic, anti-repugnance, antifungal, antioxidant and cure for other allergic dermatitis (Ivanovska et al 1995;Choi et al 2006;Mani et al 2006). Similar to the trend in lysozyme activities and hematocrit in this study, high inclusion of flavonoids has been reported to decrease hematocrit value (Hasumura et al 2004).…”

Section: Discussionsupporting

confidence: 80%

Effects of dietary propolis supplementation on growth performance, immune responses, disease resistance and body composition of juvenile eel, Anguilla japonica

et al. 2011

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This study was conducted to investigate the effects of dietary propolis supplementation on growth performance, immune responses, disease resistance and body composition of juvenile eel, Anguilla japonica, in order to evaluate its bioavailability as a feed additive for this species. A total of 540 fish averaging 7.7 ± 0.22 g (mean ± SD) were randomly distributed into 18 tanks in groups of 30, and each tank was then randomly assigned to one of three replicates of six diets containing 0 (P 0 ), 0.25 (P 0.25 ), 0.5 (P 0.5 ), 1.0 (P 1 ), 2.0 (P 2 ) and 4.0 (P 4 ) % dietary propolis. At the end of 12 weeks of feeding trial, weight gain (WG), specific growth rate (SGR), feed efficiency (FE) and protein efficiency ratio (PER) of fish fed P 0.5 diet were significantly higher than those of fish fed P 0 , P 1 , P 2 and P 4 diets (P \ 0.05). These parameters were 148.9%, 0.72% day -1 , 94.4% and 2.9, respectively for fish fed P 0.5 diet. Serum lysozyme activity of fish fed P 0.5 (105.7 units mL -1 ) and P 1 (106.0 units mL -1 ) diets were significantly higher than those of fish fed P 0 , P 0.25 , P 2 and P 4 diets. Mucus lysozyme activity of fish fed P 1 (8.4 units 10 cm -2 ) diet was significantly higher than those of fish fed P 0 , P 2 and P 4 diets. Results indicated that the optimum dietary propolis supplementation levels could be 0.25-0.5% for optimum growth and feed efficiency, and 0.5-1% for enhanced immune responses and disease resistance in eel, A. japonica. This study may suggest that the dietary propolis level for the optimum immune responses could be higher than the level for the optimum growth of eel.

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Section: Discussionsupporting

confidence: 80%

Effects of dietary propolis supplementation on growth performance, immune responses, disease resistance and body composition of juvenile eel, Anguilla japonica

et al. 2011

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“…Moreover, the co-treatment with antioxidant propolis significantly restored cell viability and reduced oxidant productions by suppressing Hcy toxicity. Previous studies have also revealed that the phenolic and flavonoid compounds of propolis, which play a crucial role in antioxidant capacity, have exhibited free radical scavenging activity and inhibited ROS formation in a dose-dependent manner [44,48,49]. It might be suggested that inhibition of Hcy-induced cell death is occurred by the reduction of intracellular ROS production.…”

Section: Discussionmentioning

confidence: 99%

Turkish propolis supresses MCF-7 cell death induced by homocysteine

Tartik

Darendelioğlu

Aykutoğlu

et al. 2016

Biomedicine & Pharmacotherapy

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“…Da Silva et al (2006) sugerem que os fl avonóides desempenham importante papel na atividade antioxidante de extratos de própolis brasileira, mas outros fatores poderiam estar envolvidos (Choi et al, 2006). Embora estudos com extratos etanólicos de própolis sejam mais comuns, é relatado que o extrato aquoso possui uma boa atividade antioxidante, associada ao alto teor de compostos fenólicos (Mani et al, 2006;Vicentino & Menezes, 2007).…”

Section: Antioxidanteunclassified

Própolis: atualizações sobre a química e a farmacologia

Lustosa¹,

Galindo²,

Nunes³

et al. 2008

Rev. bras. farmacogn.

114

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RESUMO:Própolis é uma mistura complexa, formada por material resinoso e balsâmico. Sua composição química é complexa e variada, estando relacionada com a fl ora de cada região visitada pelas abelhas e com o período de coleta da resina. Inclui fl avonóides, ácidos aromáticos, terpenóides e fenilpropanóides, ácidos graxos e vários outros compostos. A própolis tem sido objeto de intensos estudos farmacológicos e químicos nos últimos 30 anos. Em várias partes do mundo é indicada para melhorar a saúde e prevenir doenças. Atualmente, é disponível em várias formas farmacêuticas como cápsulas, extratos, enxaguatório bucal, na forma de pó, entre outras. Ainda são necessários estudos correlacionando a composição química com a atividade biológica, defi nindo cada tipo de própolis com a sua aplicação terapêutica. É uma tarefa imprescindível para um mercado cada vez maior e exigente em todo o mundo.Unitermos: Própolis, constituintes químicos, atividade biológica.ABSTRACT: "Propolis: updates on chemistry and pharmacology". Propolis (bee glue) is a complex mixture, formed by resinous and balsamic material. Its chemical composition is variable and complex, being related with the fl ora of each region visited by the bees and with the period of resins collection. Flavonoids, aromatic acids, terpenoids and phenylpropanoids, fatty acids, and other compounds are found in propolis. In the last 30 years, propolis has become subject of intense pharmacological and chemical studies. In different parts of the world it is indicated to improve health and prevent illnesses. Currently, it is available in some pharmaceutical forms as capsules, extracts, mouthrinses, powder form, among others. Indeed, studies correlating the chemical composition with the biological activity are necessary, defi ning each type of propolis with its therapeutic application. It is an essential task for a market ever bigger and demanding in the whole word.

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Propolis: Effect of different concentrations, extracts and intake period on seric biochemical variables

Cited by 99 publications

References 25 publications

Effects of dietary propolis supplementation on growth performance, immune responses, disease resistance and body composition of juvenile eel, Anguilla japonica

Effects of dietary propolis supplementation on growth performance, immune responses, disease resistance and body composition of juvenile eel, Anguilla japonica

Turkish propolis supresses MCF-7 cell death induced by homocysteine

Própolis: atualizações sobre a química e a farmacologia

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