This article develops a Professional Mobilization Framework to guide research and discussion of the mobilization of nonprofit professionals in issue politics. We use the framework, together with literature on women clergy, to develop expectations about the issue interests and political mobilization of women clergy. We use qualitative interview data and aggregate survey data from 54 women clergy to test the expectations developed in the framework. The results of the study show that the women's issue agendas focus on racism and intolerance, poverty, and gay rights, while their action agendas stress poverty, community organizing, and reproductive rights. Organizational mobilization and ease of entry appear to push women clergy into far more poverty and community-organizing activities than would be expected based on their interest in these issues alone. Meanwhile, organizational demobilization appears to result in less activity than interest on issues such as gay rights, women's rights, and racism.Rabbi Laura Goldstein 1 sits on a community board of directors for a local hospital, a position that often finds her lobbying at the state capital to raise funds and awareness about organization donations, emergency services, and blood drives. Reverend Susan Martin has been very involved with the cause of abortion rights by demonstrating, lobbying, and testifying before state legislative Note: We would like to thank Steven Rathgeb Smith and the anonymous reviewers for helpful suggestions about this article. We would also like to acknowledge research support from the Creighton University Graduate School, research assistance from Christi Braun and Kristin Kadleck, and transcription assistance from Joleen Richwine. We also thank the many women clergy who agreed to share information with us. Without their cooperation, this project would not have been possible. Nonprofit and Voluntary Sector Quarterly, vol. 30, no. 2, June 2001 321-350 © 2001 Sage Publications 321 committees on behalf of a religious pro-choice organization. Reverend Annette Wilson oversees a multitude of social services that are provided through various ministries of her congregation. Reverend Jane Smith chose to serve in a working-poor neighborhood near the inner city; she sees it as an essential element of her ministry to be a voice for the people who live in her church's neighborhood by serving on various city coalitions and task forces.As each of these examples illustrates, nonprofit professionals-in this case, professional women clergy-often participate in activities that shape public policy. Much has been written about how policy making and policy implementation are shaped by nonprofit organizations through the activities of interest groups, policy networks, and advocacy coalitions (Berry, 1999). Likewise, research has focused on understanding the capabilities and limitations of nonprofit organizations that wish to serve as effective components of a civil society that contributes to a pluralistic democracy. Similar questions about the role of nonprofit ...