Prospective assessment of risk of bacteremia with colonoscopy and polypectomy

Abstract

A prospective assessment was made of the frequency of positive blood cultures in patients undergoing colonoscopy with or without polypectomy. A total of 270 patients underwent 280 colonoscopies, of these, there were 105 patients that had 111 polypectomies. Blood cultures were taken prior to and within 15 min following each procedure. Six of 280 (2.1%) preprocedural blood cultures were positive. Seven of 169 (4%) blood cultures were positive within 15 min of insertion of the colonoscope in the colonoscopy only group. Eight of 223 (3.6%) blood cultures were positive within 10 min of the polypectomy. There was no clinical evidence of sepsis during the 24 hr following these procedures. In order to determine appropriate postprocedural sampling intervals, we induced a Staphylococcus epidermidis bacteremia with a mean of 1.16 X 10(6) colony forming units/ml on 10 occasions in seven dogs. Within 30 min of inoculation, we were able to detect only one colony forming unit/ml. The rate of positive blood cultures during colonoscopy alone and following polypectomy during colonoscopy is comparable to other gastrointestinal endoscopy procedures. The most optimal time to collect blood cultures in order to detect transient bacteremia is as soon after the procedure as is feasibly possible.

Features of electrocoagulation syndrome after endoscopic submucosal dissection for colorectal neoplasm

“…9 Originally, definition of PECS and postpolypectomy syndrome has not been clearly defined; we thought that the definition in the study by Jung et al had a possibility of 19 and bacteremia associated with colonoscopy. 20,21 Therefore, we adopted localized abdominal tenderness as a requirement for definition of PECS, and our definition is more restricted than the previous one. Additionally, our study period was later than in the previous study, and our institution had experienced about 300 colorectal ESD cases at the beginning of the study.…”

Transmission of Infection by Flexible Gastrointestinal Endoscopy and Bronchoscopy

“…), and enterococci (248). The reported incidence of bacteremia after colonoscopy, with or without biopsies and polypectomies, ranges from 0% to 25% (249)(250)(251)(252)(253)(254)(255)(256)(257). In immunocompetent patients, bacteremia during or after lower GI endoscopic procedures is usually transient and asymptomatic.…”

Veillonella parvula Discitis and Secondary Bacteremia: a Rare Infection Complicating Endoscopy and Colonoscopy?

“…Much of the research dates from the 1970s and 1980s, when blood culture systems may not have been as effective as those used today. The incidence of bacteremia in those studies ranged from 0% to 4%, and potentially pathogenic organisms were rarely isolated (13,14,18). There have been no reports of Veillonella bacteremia following colonoscopy.…”