Prospective longitudinal study of rotavirus infections in children from birth to two years of age in Central Africa

Georges‐Courbot, Marie‐Claude; Monges, J; Beraud-Cassel, A. M.; Gouandjika, I.; Georges, A. J.

doi:10.1016/s0769-2617(88)80077-7

Cited by 34 publications

(12 citation statements)

References 17 publications

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“…Throughout the study period there was cocirculation of different profiles with LA and LB predominating, as reported before [35]. While LD circulated from May to August, LB was present throughout the entire period in which rotaviruses were detected (March to September).…”

Section: Rotavirus Infections Discussionsupporting

confidence: 75%

Epidemiological aspects of rotavirus infections in Minas Gerais, Brazil

Silva

Naveca²,

Carvalho³

2001

Braz J Infect Dis

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In order to develop good polices regarding public health measures and vaccine use to prevent rotavirus induced gastroenteritis, the epidemiology of the illness in various regions of Brazil is necessary. Accordingly, this study was to detect the frequency and types of rotavirus in one city in a tropical part of Brazil. This is an epidemiological survey of pediatric gastroenteritis caused by rotavirus conducted in Juiz de Fora, Minas Gerais State, Brazil. We analyzed 656 in-patient (190) and out-patient (466) stool samples from children ages 0 to 5 years during 1998. Rotavirus detection was performed using polyacrylamide gel electrophoresis (PAGE). Rotavirus was isolated from 62/190 stool samples (32.6%) from hospitalized children and 16/466 (3.4%) from outpatients. The overall rotavirus frequency in this population was 11.9%. The highest rotavirus detection was found in hospitalized children ages 6 to 24 months. Rotaviruses were detected from March to September, with a peak incidence in June (33.3%), the coldest and driest month in the region. Electrophoretic analysis identified 10 different profiles, all long and compatible with group A rotavirus, termed L A through LJ. The L B and L D profiles circulated throughout most of the study period. However, in June, when the highest detection rate occurred, the vast majority (92.5%) of the positive samples displayed the L B profile, thus suggesting an outbreak caused by this rotavirus profile. Rotavirus induced gastroenteritis is common in one tropical region of Brazil, it is an important cause of diarrhea in hospitalized children ages 6 to 24 months, it is most common during dry, cold months of the year, and it may occur in electrophoretype restricted epidemics. Such analyses throughout Brazil will assist in developing sound guidelines regarding its prevention.

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Section: Rotavirus Infections Discussionsupporting

confidence: 75%

Epidemiological aspects of rotavirus infections in Minas Gerais, Brazil

Silva

Naveca²,

Carvalho³

2001

Braz J Infect Dis

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“…Most patients were <9 months of age. These results are similar to those found in the 1980s study at Complexe Pédiatrique, Bangui ( 2 ), which were that the major serotype/genotype was G1 (71.3%), followed by G2 (15.4%) and G3 (13.3%) ( 4 ). After 25 years, the predominant circulating genotypes are G1P[8] and G1P[6] along with G2P[4] and G9P[8].…”

supporting

confidence: 89%

“…Our study provides relevant data about the genotypes of rotavirus-A from children in the Central African Republic, 25 years after the most recent study ( 2 ). These data represent baseline information that will help with monitoring for potential changes in genotype prevalence after the introduction of rotavirus-A vaccine in the Central African Republic.…”

mentioning

confidence: 98%

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Rotavirus Epidemiology in Bangui, Central African Republic, 20081

Gouandijka-Vasilache¹,

Manirakiza²,

Gody³

et al. 2014

Emerg. Infect. Dis.

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“…Thus, there is an inversion of the migration order of gene segments 10 and 11. Genotype G2 strains generally have short RNA patterns, whereas genotype G1, G3, and G4 strains almost always have long RNA patterns [10][11][12]. Most strains of genotype G9 and G12 rotaviruses also have long RNA patterns.…”

Section: Introductionmentioning

confidence: 99%

Molecular characterization of VP7 gene of human rotaviruses from Bangladesh

Ahmed

Mitui

et al. 2010

Virus Genes

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This study was carried out during July 2005-June 2006, to characterize rotaviruses circulating in Bangladeshi children less than 5 years attended a peri-urban hospital. The proportion of rotavirus diarrhea was 39.5%. Genotype G2 was dominant (45.5%) followed by G1 (24.8%), G12 (9.6%), G9 (8.5%), and G4 (2.1%). G2 were mainly in combination with P[4], G1 and G9 with P[8], and G12 with P[6]. Phylogenetically Bangladeshi G1, G2, and G12 were closely related with the respective types from India, whereas Bangladeshi G9s of lineage III were with strains from Belgium and Australia. A G9 strain of lineage IV was clustered with strains from Sri Lanka and Turkey. Compared with prototype rotaviruses, Bangladeshi strains showed several amino acid substitutions at the antigenic sites of VP7. This study showed that the generation of diverse strains continued as evidenced by long G2, short G1 and G9 strains, and various combinations of G and P types.

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Prospective longitudinal study of rotavirus infections in children from birth to two years of age in Central Africa

Cited by 34 publications

References 17 publications

Epidemiological aspects of rotavirus infections in Minas Gerais, Brazil

Epidemiological aspects of rotavirus infections in Minas Gerais, Brazil

Rotavirus Epidemiology in Bangui, Central African Republic, 20081

Molecular characterization of VP7 gene of human rotaviruses from Bangladesh

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