Over the past decade, the specialty of prosthodontics has witnessed a great deal of advancement in its treatment mechanics to improve the quality of complete dentures. Along with proper fabrication, various approaches such as retention by overdentures and the use of implants were widely used. Along with these, many patients use adhesive materials to increase the perceived sense of satisfaction. Whereas for patient well-being, long-term use of adhesives materials is not advocated or recommended in clinical practice. This review discusses various features, trends, and the need for clinical consideration for the application of denture adhesives in prosthodontic practice.