Prospective Study to Determine Possible Correlation Between Arterial and Venous Blood Gas Values

Khan, Zahid Hussain; Samadi, Shahram; Sadeghi, Mostafa; Alemohammad, Mahmood; Zanjani, Amir Poya; Adine-Hashtjin, Shahin; Makarem, Jalil

doi:10.1016/s1875-4597(10)60045-8

Cited by 16 publications

(12 citation statements)

References 8 publications

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“…For the assessment of pH, there were 1747 subjects from 15 studies (comprising 21 datasets) that compared PVBG with ABG. 1,4,5,13,[17][18][19][20][21][22][23][24][25][26][27][28] All studies provided details on sampling technique and the time between PVBG and ABG analysis (universally described as 'minimal'). The populations ranged from healthy control participants to those that were acutely ill. Statistical heterogeneity was considerable (I 2 = 85%, Chi 2 = 158, df = 20, P < 0.0001).…”

Section: Comparison Of Ph Estimationsmentioning

confidence: 99%

“…There were 16 studies (21 datasets) with a total of 1768 subjects that compared PCO2 obtained from PVBG and ABG analysis. 1,5,13,17,[19][20][21][23][24][25][26][27][28][29][30][31] There was no appreciable difference between peripheral venous and arterial collection technique other than anatomical site. The meta-analysis for PCO2 results demonstrated a wide range of values.…”

Section: Comparison Of Pco2 Estimationsmentioning

confidence: 99%

“…There were 11 studies (with 16 datasets) containing a total of 1151 subjects that compared PVBG O2 with ABG samples. 13,17,20,21,[23][24][25][26][27][28][29] All studies provided details on method of blood sampling and analysis. The fraction of inspired oxygen was not stated for any study.…”

Section: Comparison Of Po2 Estimationsmentioning

confidence: 99%

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Peripheral venous and arterial blood gas analysis in adults: are they comparable? A systematic review and meta‐analysis

et al. 2014

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Peripheral venous blood gas (PVBG) analysis is increasingly being used as a substitute for arterial blood sampling; however, comparability has not been clearly established. To determine if the pH, PCO2 and PO2 obtained from PVBG analysis is comparable with arterial blood gas (ABG) analysis. A search was conducted of electronic databases as well as handsearching of journals and reference lists through December 2012 to identify studies comparing PVBG with ABG analysis in adult subjects. A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. A meta-analysis using a random effects model was used to calculate the average difference (bias) and the limits of agreement for the venous and arterial pH, PCO2 and PO2. A total of 18 studies comprising 1768 subjects were included in the meta-analysis. There was considerable heterogeneity between studies with I 2 approaching 100%. There was little difference between the pH obtained from the PVBG and the ABG, with the arterial pH typically 0.03 higher than the venous pH (95% confidence interval 0.029-0.038). The venous and arterial PCO2 were not comparable because the 95% prediction interval of the bias for venous PCO2 was unacceptably wide, extending from −10.7 mm Hg to +2.4 mm Hg. The PO2 values compared poorly, the arterial PO2 typically 36.9 mm Hg greater than the venous with significant variability (95% confidence interval from 27.2 to 46.6 mm Hg). PVBG analysis compares well with ABG analysis for pH estimations in adults but not to the PCO2 or PO2. These differences are sufficiently large to be of clinical significance.

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Section: Comparison Of Ph Estimationsmentioning

confidence: 99%

Section: Comparison Of Pco2 Estimationsmentioning

confidence: 99%

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Peripheral venous and arterial blood gas analysis in adults: are they comparable? A systematic review and meta‐analysis

et al. 2014

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“…First, the lactic acid level (the outcome in our study) was measured in peripheral venous blood. Venous and arterial blood might show inconsistent lactic acid levels, pH, bicarbonate, and base excess in a blood gas analysis . However, venous and arterial lactate acid levels were both significantly associated with poor outcomes in patients with shock .…”

Section: Limitationsmentioning

confidence: 98%

Association between venous blood lactate levels and differences in quantitative capillary refill time

Sato

Nogaki

et al. 2018

Acute Medicine & Surgery

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AimCapillary refill time has been widely adopted for clinical assessment of the circulatory status of patients in emergency settings. We previously introduced quantitative capillary refill time and found a positive association between longer quantitative capillary refill time and higher lactate levels in the intensive care units, but not in the emergency department. In this study, we aimed to identify a quantitative and clinically applicable index of circulatory status (ΔA b) that can be measured with quantitative capillary refill time, then evaluated the linear association between this index and lactate levels in the emergency department.MethodsWe undertook a prospective single‐center observational study at a university hospital from November 2015 to July 2016. We included 139 patients with endogenous diseases to test the association between quantitative capillary refill time, ΔA b (measured with a pulse oximeter), and lactate levels.ResultsΔA b was independently and significantly associated with high lactate levels (odds ratio [95% confidence interval]: 0.16 [0.05–0.45]).ConclusionsWe introduced ΔA b, measured using quantitative capillary refill time, as a surrogate index of lactate levels to overcome the shortcomings of capillary refill time. We showed that ΔA b is a feasible, non‐invasive, and rapid assessment of patients with high lactate levels in emergency primary care settings. Future multicenter studies with a longitudinal design should be undertaken to verify our findings.

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“…Microsampling methods currently used clinically for pediatric patients include dried blood spots (DBS) for neonatal screening of metabolic and inherited diseases, and capillary microsampling is used for small-volume POCT for capillary glucose, capillary ketones, and blood gases. [57][58][59][60] Newer forms of microsampling hold potential for the quantitation of drugs in biologic samples, and these include dried plasma spots (DPS), volumetric absorptive microsampling (VAMS), solid-phase micro-extraction (SPME), and plasma preparation technologies (PPT). Capillary microsampling has the potential to expand its current use from POCT into the quantitative analysis of drugs.…”

Section: Microsampling Techniques and Application To Antibioticsmentioning

confidence: 99%

Uncertainty in Antibiotic Dosing in Critically Ill Neonate and Pediatric Patients: Can Microsampling Provide the Answers?

Dorofaeff

Bandini

Lipman

et al. 2016

Clinical Therapeutics

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Prospective Study to Determine Possible Correlation Between Arterial and Venous Blood Gas Values

Abstract: Venous blood gas values are an acceptable alternative to arterial blood gas values in patients undergoing lumbar disc surgery.

Cited by 16 publications

References 8 publications

Peripheral venous and arterial blood gas analysis in adults: are they comparable? A systematic review and meta‐analysis

Peripheral venous and arterial blood gas analysis in adults: are they comparable? A systematic review and meta‐analysis

Association between venous blood lactate levels and differences in quantitative capillary refill time

Uncertainty in Antibiotic Dosing in Critically Ill Neonate and Pediatric Patients: Can Microsampling Provide the Answers?

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