Prostate angiosarcoma: is there any association with previous radiation therapy?

Khaliq, Waseem; Meyer, Christian F.; Uzoaru, Ikechukwu; Wolf, Richard M.; Antonarakis, Emmanuel S.

doi:10.1111/j.1464-410x.2012.11202.x

Cited by 7 publications

(2 citation statements)

References 38 publications

(50 reference statements)

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“…Our case developed prostate angiosarcoma 5 years after receiving radiation therapy and satisfies these criteria. A more recent review did not reveal a strong association between radiation therapy and prostatic angiosarcoma but did not rule out the possibility [6]. …”

Section: Discussionmentioning

confidence: 99%

Angiosarcoma of the Prostate Gland following Brachytherapy for Prostatic Adenocarcinoma

2015

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Prostatic adenocarcinoma is the most common cancer in men, but only a handful of cases of prostatic angiosarcoma have been reported in the literature. Prior radiation therapy for prostatic adenocarcinoma has been hypothesized to be a risk factor for angiosarcoma. The increasing practice of prostate cancer screening and the use of radiation therapy for management of prostatic adenocarcinoma will likely lead to more cases of prostatic angiosarcoma. Diagnosis is made by tissue sampling. Optimal management of these aggressive tumors remains to be defined and outcomes are poor with a high 1-year mortality. Primary care physicians and urologists should be aware of this rare entity and refer these patients to specialist centers where they can be managed by a multidisciplinary team. We report a case of angiosarcoma of the prostate gland diagnosed in a male presenting with lower urinary tract symptoms 5 years after brachytherapy for prostate adenocarcinoma.

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Section: Discussionmentioning

confidence: 99%

Angiosarcoma of the Prostate Gland following Brachytherapy for Prostatic Adenocarcinoma

2015

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“…37,38 Patients varied largely in age with a mean of 40 years, with one case reported in a 2-year-old child, ranging up to 80 years. [37][38][39][40][41][42][43] Two patients were in their 30s. 41,42 In one of the cases, the angiosarcoma was an element of a prostatic teratoma.…”

Section: Rhabdomyosarcomamentioning

confidence: 99%