Prostate Cancer Distribution in Patients Diagnosed by Transperineal Template-Guided Saturation Biopsy

Merrick, Gregory S.; Gutman, Sarah; Andreini, Hugo; Taubenslag, Walter; Lindert, David L.; Curtis, Rodney; Adamovich, Edward; Anderson, Richard L.; Allen, Zachariah A.; Wallner, Kent E.

doi:10.1016/j.eururo.2007.02.041

Cited by 120 publications

(102 citation statements)

References 28 publications

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“…6 All biopsies were performed by a single operator (GM). Two days before the procedure, Tamsulosin (0.8 mg daily) was initiated and was continued for 2 weeks.…”

Section: Methodsmentioning

confidence: 99%

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Performance of transperineal template-guided mapping biopsy in detecting prostate cancer in the initial and repeat biopsy setting

Taira

Merrick

Galbreath

et al. 2009

Prostate Cancer Prostatic Dis

262

171

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Transrectal ultrasound (TRUS) biopsy can miss 20-30% of clinically significant cancers. We evaluate an alternative approach-transperineal template-guided mapping biopsy (TTMB) in the initial and repeat biopsy setting. From January 2005 through September 2008, 373 consecutive men underwent TTMB (294 men with X1 prior negative biopsy and 79 men as the initial biopsy). The location of each positive biopsy core, number of positive cores, and percent involvement of each core was recorded. Cancer detection rate for the initial biopsy was 75.9%. For men with 1, 2, and X3 prior negative biopsies detection rates were 55.5%, 41.7%, and 34.4%, respectively. In all, 55.5% of the cancers identified were Gleason X7. The majority of the cancers were multifocal. There was no significant change in the number of positive cores or Gleason score as the number of prior biopsies increased. The anterior and apical aspects of the prostate were among the most common cancer locations. TTMB provides a high rate of cancer detection as initial and repeat biopsy. TTMB was particularly effective at diagnosing anterior and apical cancer. TTMB may have particular application for men considering active surveillance, with prior negative TRUS biopsies, and those considering subtotal gland or other minimally invasive treatments.

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“…6 All biopsies were performed by a single operator (GM). Two days before the procedure, Tamsulosin (0.8 mg daily) was initiated and was continued for 2 weeks.…”

Section: Methodsmentioning

confidence: 99%

“…For each biopsy core, the template coordinate and the offset from base were recorded. Biopsy regions included posterior prostate (3,4,12,13,21,22), posterior lateral (2,5,11,14,20,23), anterior lateral (1,6,9,10,15,16), anterior apex (19,24), and TZ (7,8,17,18) After completion of all sampling, patients underwent cystoscopic evaluation.…”

Section: Methodsmentioning

confidence: 99%

Performance of transperineal template-guided mapping biopsy in detecting prostate cancer in the initial and repeat biopsy setting

Taira

Merrick

Galbreath

et al. 2009

Prostate Cancer Prostatic Dis

262

171

View full text Add to dashboard Cite

show abstract

“…The benefits of increasing the number of biopsy cores and/or expanding the number of regions sampled have been demonstrated previously (5,6); however, it has also been suggested that a 10-to 12-core initial biopsy may miss PCa in almost a third of cases (7,8). Saturation prostate biopsy, which consists of ≥20 cores, has been developed to improve the detection rate of PCa in the context of repeat biopsies, radically altering the general concept of prostate biopsy (9)(10)(11)(12).…”

Section: Introductionmentioning

confidence: 99%

Analysis of repeated 24-core saturation prostate biopsy: Inverse association between asymptomatic histological inflammation and prostate cancer detection

et al. 2016

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“…The sextant biopsy scheme was initially proposed by Hodge et al (9) in 1989 and since then, this technique has been widely applied by clinicians. However, studies have since determined that the detection rate of the sextant biopsy scheme is only 20-30%, due to the smaller number of needle punctures performed (19,20). Subsequently, a 12-core biopsy was created on the basis of the sextant biopsy scheme by adding one puncture point on each side of the bottom, middle and apex of the peripheral zone in the prostate of patients, and the positive detection rate subsequently increased to 44% (21).…”

Section: Discussionmentioning

confidence: 99%

Preliminary study on ultrasound-guided prostate biopsy specimen scores

Zhan

Zhang

et al. 2017

Experimental and Therapeutic Medicine

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Abstract. Prostate cancer (PCa) is the second most frequently diagnosed cancer in males worldwide and resulted in ~258,000 cases of cancer-associated mortality in 2008. The present study visually determined the pathology scores of PCa specimens by taking into account five characteristics, including the hardness, color, plumpness, transparency and uniformity of specimens. The current study also aimed to identify the association between pathology scores and prostate specific antigen (PSA) levels, in order to reduce the complications caused by punctures and elevate the specimen positive rates. A total of 1,608 specimens from 268 patients were analyzed by one sonographer, one urologist and one pathologist. A standard pathological examination was performed on the PCa biopsy specimens and specimen scores were recorded under double-blinded conditions. A receiver operator characteristic curve identified a linear correlation between the visually determined score and PSA levels (r=0.255; P<0.001). Furthermore, logistic regression analysis indicated that the visually determined score and PSA were correlated with the diagnosis of PCa. Additionally, the authenticity of the visually determined score was higher than PSA in the diagnosis of PCa, with the best sensitivity and specificity of the visually determined scores used to predict PCa being 0.817 and 0.931, respectively.

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Prostate Cancer Distribution in Patients Diagnosed by Transperineal Template-Guided Saturation Biopsy

Cited by 120 publications

References 28 publications

Performance of transperineal template-guided mapping biopsy in detecting prostate cancer in the initial and repeat biopsy setting

Performance of transperineal template-guided mapping biopsy in detecting prostate cancer in the initial and repeat biopsy setting

Analysis of repeated 24-core saturation prostate biopsy: Inverse association between asymptomatic histological inflammation and prostate cancer detection

Preliminary study on ultrasound-guided prostate biopsy specimen scores

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