Prostatic carcinoma metastasis to the penis—an uncommon site

Ansari, Hidayath; Prashant, Ravi; Franks, Alison H.

doi:10.1016/s1470-2045(03)01251-8

Cited by 22 publications

(24 citation statements)

References 8 publications

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“…Primary tumor generally involved the genitourinary tract (69%) followed by gastrointestinal cancer (19%). All described cases were associated with very poor prognosis—variable survival rates from 1 to 24 months—and in all these cases, autopsy has identified multiple coexistent sites of metastasis in the patients [5], [6], [7]. Only 2 articles from the recent literature have described a penile metastatic localization from osteosarcoma and cholangiocarcinoma [8], [9].…”

Section: Discussionmentioning

confidence: 99%

“…Classification for prostatic cancer is made using the Gleason score, based on the degree of glandular differentiation and the pattern of tumor growth (stromal component), as identified at relatively low magnification [10]. Despite the proximity and his rich vascularization, prostate carcinoma reaches the penis infrequently: in 219 cases of penis metastases reported in the literature, only 26 cases were secondary to prostatic cancer [5], [11].…”

Section: Discussionmentioning

confidence: 99%

“…In the natural history of disseminated prostate cancer, penile metastasis may be a late presentation, and it is generally associated with very poor prognosis: the literature reports that 41% of patients died within 6 months after the diagnosis [5], [12].…”

Section: Discussionmentioning

confidence: 99%

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Relevance of computed tomography and magnetic resonance imaging for penile metastasis after prostatectomy: uncommon case report and brief review of the literature

Fiaschetti

Liberto

Claroni

et al. 2016

Radiology Case Reports

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Penile metastasis from prostate cancer represents a rare condition, associated with poor prognosis. In the literature, authors have reported less than 500 cases of secondary penile cancers, and among these cases of metastases, only 33% are from prostate cancer. Overall reported rate of survival is about 1-24 months. Here, we present an uncommon case of penile metastasis from prostatic adenocarcinoma, with particular focus on the role of computed tomography and magnetic resonance imaging in diagnosis and follow-up.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Relevance of computed tomography and magnetic resonance imaging for penile metastasis after prostatectomy: uncommon case report and brief review of the literature

Fiaschetti

Liberto

Claroni

et al. 2016

Radiology Case Reports

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show abstract

“…It should be taken into account that, at this stage of the disease, a radical or curative treatment is not possible, and androgen deprivation therapy or chemotherapy and new hormonal drugs are the basis of the treatment [2, 10]. For local metastasis disease the possibilities varied among the authors: local brachytherapy [12], local endoscopic resection of the urethral tumour [13], urethrectomy, or penectomy [11].…”

Section: Discussionmentioning

confidence: 99%

Palliative Surgery for Rare Cases of Anterior Urethral Metastasis in Prostate Cancer

Gómez

Aznar

Rodríguez

et al. 2014

Case Reports in Urology

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Penis metastasis from prostate cancer is very rare, and its management varies from case to case as there are very few cases reported in the literature. We describe a patient with prostate cancer treated with radiotherapy and androgen deprivation therapy who presented with urethral bleeding as a symptom of anterior urethral metastasis during followup. We propose a way to manage this and review the literature.

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“…The penis is an unusual site of metastasis, despite its rich and complex vascularity [1,2]. The first description of a penile metastasis was published in 1870 [3], but the first and most extensive review was carried out in 1961 by Abeshouse et al [4].…”

Section: Penile Metastasis From a T1b Prostate Carcinoma Introductionmentioning

confidence: 99%

Penile Metastasis from a T1b Prostate Carcinoma

Cai

Salvadori²,

Nesi³

et al. 2007

Oncol Res Treat

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Penile metastasis from incidental prostate carcinoma has not been described to date. Case Report: The case of a 72-year-old man affected by penile metastasis from incidental prostate carcinoma is described. In March 1998, the patient underwent prostate surgery for lower urinary tract symptoms related to benign prostatic obstruction. Histological examination revealed an incidental adenocarcinoma of the prostate. The pre-operative prostate-specific antigen (PSA) value was 3.6 ng/ml. A prostate biopsy in the peripheral prostate lobes was negative. PSA progressively rose to 8 ng/ml. The prostate biopsy was repeated and was still negative. The patient was subjected to radiotherapy, as a result of which his PSA fell to 0.7 ng/ml. 4 years after prostatectomy, the PSA rose again and the patient underwent hormonal therapy. The PSA fell to < 0.001 ng/ml. In May 2004, the patient reported a painful, erythematous nodule on his penis glans. Surgical biopsy showed a metastasis from prostate adenocarcinoma and he underwent partial penectomy. Due to disease progression, the patient underwent medical therapy. PSA and testosterone were always at minimum levels. 20 months later the patient died. Conclusion: We underline the uncertainty of the biological behaviour and optimal management of incidentally identified prostate carcinoma. In addition, we highlight that biological and clinical progression could be the consequence of inadequate treatment recommendations.

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Prostatic carcinoma metastasis to the penis—an uncommon site

Cited by 22 publications

References 8 publications

Relevance of computed tomography and magnetic resonance imaging for penile metastasis after prostatectomy: uncommon case report and brief review of the literature

Relevance of computed tomography and magnetic resonance imaging for penile metastasis after prostatectomy: uncommon case report and brief review of the literature

Palliative Surgery for Rare Cases of Anterior Urethral Metastasis in Prostate Cancer

Penile Metastasis from a T1b Prostate Carcinoma

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