2015
DOI: 10.1016/j.cmi.2015.01.012
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Prosthetic joint infection due to Enterococcus sp treated with debridement, antibiotics and retention of the implant (DAIR)

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Cited by 6 publications
(7 citation statements)
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“…Adherence to the time-limits outlined in international guidelines for debridement in this group were good (median 21 days, IQR 17-28), possibly explaining some of the results [5,11]. These results support the suggestions in the reports by Duijf [15] and Tornero [16], that standardized treatment algorithms are essential, and that adequate results can be achieved with strict adherence. We found no support for the suggestions that initial debridement could jeopardize the treatment results if implant exchange is needed later on.…”
Section: Discussionsupporting
confidence: 83%
See 1 more Smart Citation
“…Adherence to the time-limits outlined in international guidelines for debridement in this group were good (median 21 days, IQR 17-28), possibly explaining some of the results [5,11]. These results support the suggestions in the reports by Duijf [15] and Tornero [16], that standardized treatment algorithms are essential, and that adequate results can be achieved with strict adherence. We found no support for the suggestions that initial debridement could jeopardize the treatment results if implant exchange is needed later on.…”
Section: Discussionsupporting
confidence: 83%
“…International Publisher debridement with implant retention, which is the preferred modality for most staphylococcal and Gram-negative early or acute hematogenous PJIs, no clear recommendation exists as of yet. Reports on this procedure in enterococcal PJI, however, have presented acceptable results in selected patient populations [15,16].…”
Section: Ivyspringmentioning
confidence: 99%
“…In our study, failures were subclassified as treatment or clinical failure and success, respectively. Considering these definitions, the eradication of enterococcal PJI (treatment success) in our cohort was 83.7%, which was higher than previously reported (50 to 76%) [1, 9, 12, 27]. However, as 11 patients experienced new infection with another microorganism or were culture-negative, the infection-free probability (clinical success) was only 67.5%.…”
Section: Discussioncontrasting
confidence: 50%
“…This fact represents the main limitation of the study. Other studies reported low clinical success with debridement and retention such as 40% [9], 47% [27], 50% [1] and 66% [11] and based on this observation two-stage prosthesis exchange is recommended for enterococcal PJI. However, with improved antimicrobial therapy, debridement and retention or one-stage prosthesis exchange may become an alternative to two-stage exchange with high treatment success.…”
Section: Discussionmentioning
confidence: 94%
“…The success rate was between 62 and 66% which was considered far from the 88% success rate obtained in staphylococcal infections treated with DAIR and a combination of levofloxacin and rifampin. At the end of this study, the author stated the importance of finding a fixed antibiotic regimen for PJI due to Enterococcus species [11].…”
Section: Discussionmentioning
confidence: 99%