Prosthetic Valve Endocarditis

Mahesh, Balakrishnan; Angelini, Gianni D; Caputo, Massimo; Jin, Xu Yu; Bryan, Alan J.

doi:10.1016/j.athoracsur.2004.11.001

Cited by 93 publications

(68 citation statements)

References 56 publications

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“…W przypadku infekcji okołooperacyjnej zakażenie zazwyczaj obejmuje miejsce połączenia między wszytym pierścieniem sztucznej zastawki a pierścieniem natywnym, co prowadzi do powstania ropni okołozastawkowych, niestabilności protezy, pseudotętniaków i przetok [339,343,344]. W późnym PVE mogą współistnieć dodatkowe mechanizmy.…”

Section: Definicja I Patofizjologiaunclassified

2015 ESC Guidelines for the management of infective endocarditis

Habib¹,

Lancellotti

Antunes³

et al. 2015

Kardiol Pol

148

212

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Section: Definicja I Patofizjologiaunclassified

2015 ESC Guidelines for the management of infective endocarditis

Habib¹,

Lancellotti

Antunes³

et al. 2015

Kardiol Pol

148

212

View full text Add to dashboard Cite

“…[2][3][4][5] Prosthetic valve endocarditis is an infrequent, but potentially lethal event, occurring primarily in the aortic and mitral positions. [6][7][8][9][10][11][12] Prosthetic valve endocarditis is usually preceded by systemic bacteremia, with subsequent infection at the site of the prosthesis. Both native and prosthetic pulmonic valve endocarditis are rare, with reported incidences of 0.6% to 1% 13 and 1.2% to 2%, 14,15 respectively.…”

mentioning

confidence: 99%

Bloodstream Infections Occurring in Patients With Percutaneously Implanted Bioprosthetic Pulmonary Valve

Buber

Bergersen

Lock

et al. 2013

Circ: Cardiovascular Interventions

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Background-Percutaneous pulmonary valve implantation using a stent-based bioprosthetic valve provides an alternative to surgery in select patients. Systemic infections in Melody valve-implanted patients with and without identified valve involvement have been reported, yet the incidence is unknown, and risk factors remain unidentified. Methods and Results-Between 2007 and 2012, a total of 147 consecutive patients with congenital heart disease underwent Melody percutaneous pulmonary valve implantation at our institution. Demographic and clinical variables were collected at baseline and at follow-up and analyzed as predictors. The occurrence of bloodstream infection (BSI), defined as a bacterial infection treated with ≥4 weeks of antibiotics, served as our primary outcome. The mean age at implantation for the study population was 21.5±11 years, and tetralogy of Fallot was the cardiac condition in 59%. During a median followup of 19 months, 14 patients experienced BSI (9.5%; 95% confidence interval, 5.3%-15%). Of these, 4 (2.7%) patients had Melody valve endocarditis. Two patients died during the event, neither of whom had known valve involvement. The median procedure to infection time was 15 months (range, 1-56). In univariate analysis, male sex, previous endocarditis, in situ stents in the right ventricular outflow tract, and presence of outflow tract irregularities at the implant site were associated with BSI occurrence. Conclusions-In this cohort, 9.5% of patients who underwent Melody percutaneous pulmonary valve implantation experienced subsequent BSI, occurring 1 to 56 months after implant, and 2.7% of patients had prosthetic endocarditis. Our findings suggest that patient and nonvalve anatomic factors may be associated with BSI after percutaneous pulmonary valve implantation. (Circ Cardiovasc Interv. 2013;6:301-310.)

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“…Infections in mechanical valves generally involve the sewing ring or adherent thrombi, and can lead to paraprosthetic leaks, ring abscesses, and invasive infection, necessitating operative intervention. Bioprostheses are less susceptible to early infection, which is often restricted to the leaflets, making cure with antibiotics more likely but increasing the chances of late failure due to degeneration of the cusps (Mahesh et al, 2005). Severe heart failure, staphylococcal infection and complicated PVE are designated as markers of both in-hospital and late mortality, while severe heart failure and S. aureus infection were the only independent predictors of in-hospital death (Habib et al, 2008).…”

Section: Prosthetic Valve Endocarditismentioning

confidence: 99%

“…PVE is defined as infection occurring in a prosthetic heart valve and has an overall incidence of 0.32% to 1.2% per patient year and cumulative risk of 5% at 10 years (Mahesh et al, 2005). Rates range from 1% to 3% within the first year however the highest rate of infection occurs in the first three postoperative months.…”

Section: Prosthetic Valve Endocarditismentioning

confidence: 99%

“…Surgical consultation should be promptly scheduled given that periannular complications occur in more than 50% of patients and may lead to complete aortic root destruction. Radical surgical debridement with a margin of healthy tissue to eradicate intracardiac foci of infection remains the primary aim of surgery for PVE, enabling secure fixation of the new prosthesis, avoiding recurrent or residual infection, periprosthetic leak or dehiscence, or subannular aneurysm formation (Mahesh et al, 2005).…”

Section: Prosthetic Valve Endocarditismentioning

confidence: 99%

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