Prosthodontic rehabilitation of head and neck cancer patients—Challenges and new developments

Vosselman, Nathalie; Alberga, Jamie; Witjes, Max J. H.; Raghoebar, Gerry M.; Reintsema, Harry; Vissink, Arjan; Korfage, Anke

doi:10.1111/odi.13374

Cited by 41 publications

(45 citation statements)

References 52 publications

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“…In recent years, there has been a developing paradigm shift towards placement of zygomatic implants at primary maxillary tumour resection surgery as a means of accelerating prosthetic rehabilitation and potentially avoiding the issues of surgery in the irradiated field (Boyes‐Varley et al, 2007; Butterworth, 2019). Close working relationship between surgical and prosthodontic teams is mandatory to execute this treatment modality effectively (Vosselman et al, 2020). Butterworth (Butterworth, 2019) assessed the differences in survival of zygomatic implants between primary and secondary placement protocols in a larger study and found 4% failure in the primary group compared to 11% failure in the secondary group.…”

Section: Resultsmentioning

confidence: 99%

Zygomatic implant‐based rehabilitation for patients with maxillary and mid‐facial oncology defects: A review

2020

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Malignant diseases of the head and neck require radical treatment, often resulting in loss of the dentition and supporting structures, facial defects and drastic changes in anatomical form. The implications of this are life-changing, often associated with the loss or hindrance of function, speech, swallowing and appearance, leading to a detrimental effect on the patient's social and psychological wellbeing. Maxillary and mid-facial defects are complex and can be classified by level using classifications such as that by Brown and Shaw (2010) and Okay, Genden, Buchbinder, and Urken (2001) to assist in treatment planning, resection, surgical reconstruction and prosthodontic rehabilitation. In 1998, Professor PI Branemark's team developed the specifically designed zygomatic implant for use in compromised maxillary bone including severe atrophy, congenital defects and tumour resection defects (Brånemark, 1998). In 2001, his team published the first paper (Parel, Brånemark, Ohrnell, & Svensson, 2001) on the survival of these implants placed into the residual zygomatic

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Section: Resultsmentioning

confidence: 99%

Zygomatic implant‐based rehabilitation for patients with maxillary and mid‐facial oncology defects: A review

2020

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“…Planning often involves removal or treatment of foci and rehabilitation planning after surgical procedures (Spijkervet et al., 2020). Ideally, before surgery the plan for rehabilitation is defined and integrated with the surgical treatment (Alberga et al., 2020; Vosselman et al., 2020). In this perspective, the past three decades the success of placing dental implants has been established.…”

Section: Figurementioning

confidence: 99%

Cooperation as core value in an innovative era

Witjes

Vissink

2020

Oral Diseases

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Cooperation as core value in an innovative era Diagnosis, treatment, and rehabilitation of patients suffering from oral cancer are shared responsibilities of primary care givers like dentists, physicians and oral medicine specialists, and intramural secondary care specialties. Because of the complex nature of treatment and the necessity of long-term care in most patients, the treatment and follow-up of head and neck cancer patients are confined to centers with dedicated teams in most countries. Early referral of patients suspected for oral cancer is considered important because survival is related to tumor stage and primary care givers play a pivotal role in that respect (Grafton-Clarke et al., 2019). Where health care is organized with possibilities of a quick and easy referral, the risk of delayed referral is greatly reduced. dental rehabilitation after oncological surgery. Several practical issues remain to be resolved, however, such as the timing of placement of dental implants as well as the placement of dental implants in free flaps. Like for surgical planning, planning of an oral rehabilitation is supported by 3D technology. This technology supports precise placement of implants and design of prosthetic devices. Notwithstanding the long experience with dental implants, new ideas based on implant technology still emerge and become implemented in clinical practice. The application of zygoma implants after maxillectomy in combination with soft tissue flaps is an example of a creative idea finding its way into the clinic (Hackett et al., 2020). Treatment of cancer in the head and neck area is commonly accompanied by damage to the salivary glands (Barazzuol et al., 2020; Vissink et al., 2015). Damage to the salivary glands is unavoidable as the salivary glands are located superficially and the ionizing radiation has to pass salivary gland tissue to reach the tumor. While there is many approach to minimize this radiation damage to salivary gland tissue, there is yet no satisfactory therapy to treat radiation-induced salivary gland damage. A feasible option might be harvesting salivary gland tissue during, for example, a head and neck dissection procedure, isolate and proliferate stem cells from this tissue and return these stem cells to the salivary glands that are damaged by the postoperative radiotherapy. Such stem cell therapy is an attractive option for the long-term treatment of hyposalivation related xerostomia induced by irradiation, but is in need of further study in animals and preliminary studies in human before it can evolve into a clinically applicable method. Future studies should also focus on a better understanding of the radiosensitivity of parotid and submandibular salivary gland tissue (Serrano Martinez et al., 2020). All these developments show the benefits for patients of a good cooperation between primary and secondary caregivers. The good cooperation also demonstrates what can be achieved if efforts are focused and put into practice.

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“…Treatment planning varies depending on factors such as the location of the primary tumor, the stage of cancer, age and the general health of the patient. However, oncology patients are usually treated with ablative surgery, radiotherapy (RT), chemotherapy or a combination of these (10,(12)(13)(14)(15). Surgical treatment of HNC causes deformity and changes in the anatomy of the region.…”

Section: Introductionmentioning

confidence: 99%

“…Another stage of cancer treatment is to restore the function and aesthetics that the patient has lost (10). Dental and prosthetic rehabilitation can significantly improve patients' QoL after HNC treatment (18)(19)(20).…”

Section: Introductionmentioning

confidence: 99%

“…In the diagnosis, treatment and rehabilitation stages of these patients, cooperation of experts from different fields is required (7)(8)(9). Good communication between surgeons, radiation oncologists, medical oncologists and maxillofacial prostodontist should be ensured for good treatment (10,11). Treatment planning varies depending on factors such as the location of the primary tumor, the stage of cancer, age and the general health of the patient.…”

Section: Introductionmentioning

confidence: 99%

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Dental Implant Treatment In Patients With Oral Cancer: Literature Review

Avukat¹,

Akay²

2020

Osmangazi̇ Journal of Medicine

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The aim of this review is to evaluate the timing of dental implants placement and long-term survival rates in patients who have had prosthetic rehabilitation with dental implants after ablative surgery and radiotherapy (RT), and have had head and neck cancer (HNC). For this purpose; implant survival (IS) rates placed as primary/secondary or placed in bones with/without RT were evaluated. The literature published between 2000-2020 has been reviewed for the evaluation of dental implant treatment in patients with HNC. The search terms used in PubMed scans were "head and neck cancer", "oral cancer", "dental implant" and "radiotherapy". 134 related articles have been defined in PubMed database searches and 16 were included in the final analysis. Dental implant applications have gained importance in the prosthetic treatment of patients with oral cancer. In cases where conventional prosthetic treatments are insufficient, dental implants provide retention and stability to dentures. However, before starting treatment, whether the patient is receiving chemotherapy, RT and the use of bisphosphonate should be taken into consideration and the timing of the surgical procedures should be adjusted correctly. In addition, these patients should be followed up regularly for a long time.

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Prosthodontic rehabilitation of head and neck cancer patients—Challenges and new developments

Abstract: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Cited by 41 publications

References 52 publications

Zygomatic implant‐based rehabilitation for patients with maxillary and mid‐facial oncology defects: A review

Zygomatic implant‐based rehabilitation for patients with maxillary and mid‐facial oncology defects: A review

Cooperation as core value in an innovative era

Dental Implant Treatment In Patients With Oral Cancer: Literature Review

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