Prosthodontic restoration of a COVID‐19 associated mucormycosis defect: A clinical report

Abstract

Introduction Coronavirus Disease 2019 (COVID‐19) pandemic brought the clinical practice of dentistry and prosthodontics at the threshold of a new era, due to the increasing prevalence of a relative rare condition normally affecting the immunocompromised patients. Aim The aim of this clinical case report is to briefly describe the etiopathogenesis, the surgical and prosthodontic management of this evolving medical condition emphasizing the emerging role of the maxillofacial prosthodontist in restoring the patients' well‐being. Methods and Results The surgical and prosthodontic rehabilitation of a COVID‐19 infected patient with a mucormycotic lesion of the maxilla will be presented. Conclusion The role of the maxillofacial prosthodontist is important in alleviating this severe COVID‐19 associated morbidity.

Prosthodontic rehabilitation of patients with Rhinocerebral mucormycosis: An update of evidence

“…27 Recent case reports have documented 10 patients with history of post covid mucormycosis (PCM) who were efficiently rehabilitated with obturators (Table 1, Table 2). [19][20][21][22][23]28,29 Diabetes mellitus was the most significant associated risk factor in 27 patients followed by Acute Myeloid Leukemia based on data reported here and earlier by Santos et al Rhizopus oryzae has been reported to be the most common causative organism as high glucose levels, insulin resistance and ketoacidosis encourage its growth. 30 Amphotericin B remained the first-choice drug followed by Posaconazole.…”

“…5 I. E. Ali, et al reported prosthodontic rehabilitation of post mucormycosis defects from 30 case reports published between 2010 to 2021. 24 18 more patients on PubMed [17][18][19][20][21][22][23] and 9 on google scholar [Table 2] were reported with history of mucormycosis followed by fabrication of palatal obturator from 2020 to May 2023. Mean age and gender wise distribution of patients who were rehabilitated after surgical management of mucormycosis has been depicted in Figure 1.…”

“…9, 12 Artopoulou I et al used Obturator Functioning Scale and Distress Scale to evaluate the patient satisfaction and psychological status respectively. 23 Early diagnosis of condition, treatment of underlying pathology, thorough debridement, antifungal drugs, local care of post debridement wound, psychological counselling and prosthodontic rehabilitation are integral components of a comprehensive treatment plan for such patients. 25 In a breakthrough research, Sharma et al have proposed the future of intranasal sprays with anti-inflammatory, anti-diabetic and antiviral action which would help in prophylactic control of mucormycosis in covid infected and/ or diabetic patients.…”

Post-COVID-19 Rhino-Orbito-Maxillary Mucormycosis Defect: Our Surgical Experience with Single Stage Delayed Reconstruction Using Free Flap

“…The majority of the cases of post- COVID-19-associated ROM defect reported in the literature have been rehabilitated prosthetically using intraoral obturators, partial dentures, palatal flaps, and other soft-tissue flaps. 5 17 A recent study by Gupta et al 18 used ALT flaps for covering COVID-19-associated mucormycosis defects in 14 patients. All flaps in their study survived, without any major or minor complications.…”