2018
DOI: 10.1161/circulationaha.118.036697
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Protection From Cardiac Ischemia-Reperfusion Injury by Epigenetic Regulation of NADPH Oxidase

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Cited by 3 publications
(4 citation statements)
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“…Many researchers reported that cyclical and sustained stretches can trigger O 2 ˙ − release in both cultured endothelial and vascular cells, 52 which involves specific enzymes such as nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOX family) catalyzing the following reaction as shown in Fig. 4D.…”
Section: Resultsmentioning
confidence: 99%
“…Many researchers reported that cyclical and sustained stretches can trigger O 2 ˙ − release in both cultured endothelial and vascular cells, 52 which involves specific enzymes such as nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOX family) catalyzing the following reaction as shown in Fig. 4D.…”
Section: Resultsmentioning
confidence: 99%
“…Second, the potential of the composite hydrogel to absorb ROS in an ischemia‐reperfusion model was demonstrated. As the presence of ROS within the LV expands the injury, leading to extensive cell death, [ 6 , 39 , 40 , 41 , 42 ] inflammation [ 41 , 64 , 65 ] and, overall, to progressive damage, the ability to eliminate ROS may be extremely beneficial for treating MI and other heart diseases, as well as other injuries in different organs. Our results indicate that injection of the composite complex leads to cardioprotection within the LV, which, in turn, leads to the preservation of heart structure and function.…”
Section: Discussionmentioning
confidence: 99%
“…The damage from these factors is progressive, affecting the implanted tissue and jeopardizing the success of the treatment. [ 6 , 39 , 40 , 41 , 42 , 43 , 44 ]…”
Section: Introductionmentioning
confidence: 99%
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