Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis

Tognolini, Massimiliano; Ballabeni, Vigilio; Bertoni, Simona; Bruni, Renato; Impicciatore, M; Barocelli, Elisabetta

doi:10.1016/j.phrs.2007.07.002

Cited by 155 publications

(91 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Herbal drugs and essential oil of fennel has different pharmacological properties such as anti-spasmodic, anti-allergic, diuretic, antiinflammatory, analgesic and antioxidant effect (Ebeed et al, 2010, Choi and Hwang, 2004, Misharina and Polshkov, 2005, Parejo et al, 2002, Pradhan et al,2008, Kooti et al, 2015. In addition, the volatile oil showed antimicrobial and hepatoprotective (Sellam et al, 2014, Toma et al, 2008, Özbek et al, 2003, antithrombotic activity (Tognolini et al, 2007), antidiabetic activity (El-Soud et al, 2011), antitumour activity (Pradhan et al, 2008) and acaricidal activity (Lee, 2004).…”

Section: Foeniculummentioning

confidence: 99%

Antifungal potential of the Seed and Leaf Foeniculum vulgare Mill essential Oil in liquid and vapor phase against phytopathogenic fungi

Sellam¹,

Bammou²,

Ramchoun³

et al. 2015

J App Pharm Sci

View full text Add to dashboard Cite

Analysis of essential oils obtained from the seeds (SEO) and leaves (LEO) of Foeniculum vulgareMill cultivated in southeast of Morocco revealed that trans-anethole was the major constituent (54.67% of seed oil and 50.60% in leaf oil), followed by estragol (35.33% of seed oil and 30.15% in leaf oil). Other components present in leaf oil included fenchone, linalool and α-pinene, while seed oil contained fenchone, limonene and γ-terpinen. Besides, minor constituents like camphene, camphor, myrcene, pahllandrene, fenchyl acetate and β-bisabolene were obtained from seeds and leaves. The essential oils of the seeds and leaves of Foeniculum vulgare were assayed for their antifungal activity by poison food (PF) technique and the volatile activity assay (VA) against five agricultural pathogenic fungi. The results indicated that the essential oil of Foeniculum vulgare inhibited the mycelial growth of all fungal strains tested. VA assay of essential oil was consistently found to be more effective than PF technique. The mycelium growth was completely inhibited by LEO on Alternaria sp., Fusarium oxysporum f. sp. albedinis and Aspergillus brasiliensis at 0.25 µl mL -1 air. Rhizopus stoloniferawas the most sensitive with a minimal inhibitory concentration (MIC) = 0.25 µl mL -1 air.

show abstract

Section: Foeniculummentioning

confidence: 99%

Antifungal potential of the Seed and Leaf Foeniculum vulgare Mill essential Oil in liquid and vapor phase against phytopathogenic fungi

Sellam¹,

Bammou²,

Ramchoun³

et al. 2015

J App Pharm Sci

View full text Add to dashboard Cite

show abstract

“…Also, this compound was used as chemical precursor of paramethoxyamphetamine in the clandestine manufacture of amphetamines [47]. It is well known that anethole is therapeutically an important compound, which was reported to have strong anti-inflammatory, antifungal, antibacterial, and antiplatelet activities among others [48][49][50][51][52][53].…”

Section: Resultsmentioning

confidence: 99%

Chemical Composition of the Essential Oil and Antimicrobial Activity of Scaligeria DC. Taxa and Implications for Taxonomy

Baldemir¹,

Demırcı²,

Paksoy³

et al. 2017

Rec. Nat. Prod.

View full text Add to dashboard Cite

Six different Scaligeria DC. taxa (Apiaceae) essential oils (EOs) obtained by hydrodistillation from herba with the flowers collected from different sites from Turkey. The oils were analyzed and characterized by gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS) simultaneously. A total of 133 different compounds were identified and relative qualitative and quantitative differences were observed among the evaluated samples. Analytical profiles of the Scaligeria EOs showed characteristic differences in terms of different main chemical constituents, between the two taxa S. lazica Boiss. and S. tripartita (Kalen.) Tamamsch; and S. napiformis (Sprengel) Grande, S. meifolia (Fenzl) Boiss., S. capillifolia Post, S. hermonis Post, S. glaucescens (DC.) Boiss. taxa, respectively. The main component germacrene D can be utilized as marker for the chemical discrimination of the Scaligeria genus. In addition, Scaligeria EOs were evaluated in vitro for their antimicrobial activity against pathogenic Gram positive (Staphylococcus aureus and Bacillus cereus), Gram negative (Pseudomonas aeruginosa) and yeast (Candida albicans, C. parapsilosis, and C. krusei) standard strains by using a micro-dilution assay. As a general result, the oils showed moderate inhibitory range when compared with standard antimicrobial agents.

show abstract

“…13,26 Various studies conducted on these ingredients have proved that most of these test drugs possess important neuroprotective, antioxidant and anti-inflammatory actions. The flavonoid glabridin derived from Glycyrrhiza glabra (Aslus'soos) significantly decreases the volume of focal infarct, apoptosis 31 and cerebral histological damage 32 as well as antioxidant activity is also reported in Glycyrrhiza glabra has the neuroprotective effect through alteration of multiple pathways link with apoptosis 33 Essential oil from seeds of Foeniculum vulgare (Badyan) showed antithrombotic activity, thus preventing the paralysis induced by collagen-epinephrine intravenous injection 34 Another study on Badyan (Foeniculum vulgare) has been found to dissolve the blood clot after hemorrhagic stroke 35 which may be attributed to its monoamine inhibitor activity that upregulates the level of serotonin, nor-epinephrine, and dopamine in brain and thus brain plasticity is accomplished 36 Operculia turpethum 37 Cassia fistula. 38 Experimental studies concluded that Lavandula stoechas i.e.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Mā-Ul-Ūsool, Mus'hil-E-Balgham and Inkibāb With Marzanjosh in Management of Post- Stroke Disability With Respect to Adl: A Black Box Study

Alam¹,

Khalid²,

Ansari³

2017

J Biol Sci Opin

View full text Add to dashboard Cite

Falij-e-Nisfi (hemiplegia) is a disease characterized by loss of motor and sensory functions in longitudinal half of the body. The present study was conducted to evaluate the efficacy of Ma-ul-Usool (root extracts), Mus'hil-e-Balgham (phlegm purgative) and Inkibab (steam inhalation) with Marzanjosh in management of post-stroke disability with respect to Activities of Daily Living (ADL) on scientific parameters. It was an open label, pre and post without control clinical trial for the period of 30 days conducted on 29 eligible cases of hemiplegia due to stroke. Nuskha Ma-ul-Usool was administered in form of decoction once in morning on an empty stomach for 15 days; then Nuskha Mus'hil-e-Balgham was added with Ma-ulUsool and given on 13 th and 15 th day of treatment in order to induce purgation. From 16 th day onwards, Inkibab (steam inhalation) was started with 20 gm of Marzanjosh once a day daily till the end of the study. The pre and post treatment values of Barthel Index Scale were analyzed by paired t test to assess ADL in the participants. Significant improvement (P<0.05) was observed in ADL of participants at the end of treatment. No side effect was observed during and after the study; overall compliance to the treatment was satisfactory. The study concluded that trial formulations have statistically significant effect in improving the ADL of post stroke disability cases.

show abstract

Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis

Cited by 155 publications

References 30 publications

Antifungal potential of the Seed and Leaf Foeniculum vulgare Mill essential Oil in liquid and vapor phase against phytopathogenic fungi

Antifungal potential of the Seed and Leaf Foeniculum vulgare Mill essential Oil in liquid and vapor phase against phytopathogenic fungi

Chemical Composition of the Essential Oil and Antimicrobial Activity of Scaligeria DC. Taxa and Implications for Taxonomy

Efficacy of Mā-Ul-Ūsool, Mus'hil-E-Balgham and Inkibāb With Marzanjosh in Management of Post- Stroke Disability With Respect to Adl: A Black Box Study

Contact Info

Product

Resources

About