Protective effect of steamed American ginseng (Panax quinquefolius L.) on V79-4 cells induced by oxidative stress

Kim, Kyung Tack; Yoo, Kyung Mi; Lee, Jin Wook; Eom, Seok Hyun; Hwang, In Kyeong; Lee, Chang Yeol

doi:10.1016/j.jep.2007.01.004

Cited by 90 publications

(56 citation statements)

References 33 publications

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“…The oxidative stresses in spleen and thymus were also reduced to a certain extent. The results are similar to the previous studies in which antioxidant activities of American ginseng and Chinese jujube were observed (Kim et al, 2007;Shen et al, 2009;Wang J.X. et al, 2012).…”

Section: Discussionsupporting

confidence: 92%

Immunomodulatory effect of a formula developed from American ginseng and Chinese jujube extracts in mice

et al. 2016

J. Zhejiang Univ. Sci. B

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Abstract:Background: American ginseng (Panax quinquefolius L.) and Chinese jujube (Zizyphus jujuba Mill.) are commonly used in traditional Chinese medicine to enhance immune function. Objective: The present study aimed to develop one Chinese prescription, Shenzao Cha (SZC), consisting of American ginseng and Chinese jujube, and systematically investigate its immunomodulation in healthy ICR mice. Methods: Normal ICR mice received intragastric administration of SZC (1.3, 2.6, and 5.2 g raw material/kg body weight) once daily for four weeks, while a control group received the same amount of sterile water. Results: SZC significantly increased the spleen and thymus indices and T-lymphocyte proliferation, while the T-lymphocyte proliferation in the 5.2 g/kg group was 1.4-fold higher than that in the control. Further, 1.3 g/kg SZC could markedly improve hemolytic activity by 25.2%, and 2.6 g/kg SZC increased the NK cell activity by 78.6% relative to the control. In addition, the activities of antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase), that participated in modulating oxidative stress, were significantly increased in the liver, spleen, thymus, and serum, while the contents of malondialdehyde were dramatically decreased. Conclusions: SZC exhibited potent immunomodulatory effects on innate and adaptive immunity in healthy ICR mice, as well as potential antioxidant activity for prevention of oxidative stress, which was suggested to partly contribute to the immune enhancement.

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Section: Discussionsupporting

confidence: 92%

Immunomodulatory effect of a formula developed from American ginseng and Chinese jujube extracts in mice

et al. 2016

J. Zhejiang Univ. Sci. B

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“…The amount of total phenolic compounds using the Folin-Ciocalteu was performed according to the method of Kim and co-workers [22]. In this experiment, the methanol extract of leaves of plants, 100% ethanol, 50% methanol, reagent Folin-Ciocalteu, Sodium bicarbonate 6% and Gallic acid standard solution were used.…”

Section: Total Phenolic Compounds Measurementmentioning

confidence: 99%

Zinc Sulphate and Nano-Zinc Oxide Effects on Some Physiological Parameters of Rosmarinus officinalis

Mohsenzadeh¹,

Moosavian²

2017

AJPS

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In the present study, the effects of foliar application of zinc sulphate and nano-zinc oxide on physiological indices (chlorophyll and carotenoids content, antioxidant activity, total phenolic content, proline, lipid peroxidation and sugar) of rosemary were evaluated. Greenhouse cultivation experiment in a randomized complete block with three levels of foliar zinc and three levels of foliar nano-zinc oxide and control treatment, each with three replications, was carried out. The results showed that low concentrations of zinc and nano-zinc oxide significantly increased chlorophyll and carotenoid compared to the control. Whereas with the high concentration of nano-zinc oxide, chlorophyll and carotenoid decreased compared to the control. Antioxidant enzymes activity increased with zinc and nano-zinc oxide compared to control plants. In addition, proline, membrane lipid peroxidation, soluble sugar and phenolic compounds increased in the treated plants. Proline and plant antioxidant enzymes to scavenge free radicals have increased. Two levels of zinc increased the total phenolic compounds of rosemary leaves significantly but nano-zinc oxide did not show a significant difference compared to the control.

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“…After cooling to room temperature, the absorbance was measured at 695 nm. Ascorbic acid was used as the standard and the total antioxidant activity was expressed as equivalents of ascorbic acid (Kim et al, 2007;Kumar et al, 2010).…”

Section: Total Antioxidantsmentioning

confidence: 99%

In vitro biological screening and chemical constituents of Euphorbia perbracteata Gage

Naidu¹,

Padma²,

Rudraraju³

2014

J. Med. Plants Res.

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To assess the in vitro biological activity and chemical constituents of Euphorbia perbracteata using different polar solvents, the phytochemical constituents were screened and total phenols, antioxidants, flavonoids content, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity and IC 50 values were calculated. Antimicrobial assay was carried out by using disc diffusion method and minimum inhibitory concentration (MIC) was determined against Gram-positive (4), Gram-negative (4) and fungal (1) human pathogenic strains. The results showed that the extracts possessed a broad spectrum of antimicrobial activity with significant MIC values which ranged from 156 to 312 µg/ml. Total phenols (5.163 ± 0.573), antioxidants (2.589 ± 0.115 mg/g Dw) and IC 50 values for DPPH free radical scavenging activity (12.953 µg/ml) was calculated. The observations substantiate the folk claims and the significant biological properties prompted to carry out further studies to isolate the bioactive principles involved in the property which is under progress.

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Protective effect of steamed American ginseng (Panax quinquefolius L.) on V79-4 cells induced by oxidative stress

Cited by 90 publications

References 33 publications

Immunomodulatory effect of a formula developed from American ginseng and Chinese jujube extracts in mice

Immunomodulatory effect of a formula developed from American ginseng and Chinese jujube extracts in mice

Zinc Sulphate and Nano-Zinc Oxide Effects on Some Physiological Parameters of Rosmarinus officinalis

In vitro biological screening and chemical constituents of Euphorbia perbracteata Gage

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