Protective effects of hydrogen rich saline solution on ventral penile mathieu type flap with penile tourniquet application in rats

Gulburun, Merve Altin; Karabulut, Ramazan; Türkyılmaz, Zafer; Eryılmaz, Sibel; Kaya, Cevdet; Arslan, Burak; Gülbahar, Özlem; Poyraz, Aylar; Sönmez, Kaan

doi:10.1016/j.jpurol.2021.01.046

Cited by 4 publications

(1 citation statement)

References 30 publications

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“…It plays an important role in microbial killing by neutrophils but is also a local mediator of tissue damage and the resulting inflammation in various inflammatory diseases [ 46 ]. As discussed above, H 2 can decrease the amount of MPO [ 47 ], which may be associated with inhibition of its release by neutrophils.…”

Section: Potential Mechanisms Of Molecular H 2 Act...mentioning

confidence: 99%

Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases

Zhang

2022

Oxidative Medicine and Cellular Longevity

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Ageing is a physiological process of progressive decline in the organism function over time. It affects every organ in the body and is a significant risk for chronic diseases. Molecular hydrogen has therapeutic and preventive effects on various organs. It has antioxidative properties as it directly neutralizes hydroxyl radicals and reduces peroxynitrite level. It also activates Nrf2 and HO-1, which regulate many antioxidant enzymes and proteasomes. Through its antioxidative effect, hydrogen maintains genomic stability, mitigates cellular senescence, and takes part in histone modification, telomere maintenance, and proteostasis. In addition, hydrogen may prevent inflammation and regulate the nutrient-sensing mTOR system, autophagy, apoptosis, and mitochondria, which are all factors related to ageing. Hydrogen can also be used for prevention and treatment of various ageing-related diseases, such as neurodegenerative disorders, cardiovascular disease, pulmonary disease, diabetes, and cancer. This paper reviews the basic research and recent application of hydrogen in order to support hydrogen use in medicine for ageing prevention and ageing-related disease therapy.

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Section: Potential Mechanisms Of Molecular H 2 Act...mentioning

confidence: 99%

Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases

Zhang

2022

Oxidative Medicine and Cellular Longevity

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Protective Effects of Hydrogen-Rich Saline on Experimental Intestinal Volvulus in Rats

Oral

Türkyılmaz

Karabulut

et al. 2022

Journal of Investigative Surgery

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Current perspectives in hypospadias research: A scoping review of articles published in 2021 (Review)

Gozar¹,

Bara²,

Dicu³

et al. 2023

Exp Ther Med

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Hundreds of papers are written about hypospadias every year referring to all aspects of the pathology, being one of the most common congenital malformations. The present study conducted a scoping review of articles published in 2021 to present the main issues and summarize current perspectives and achievements in the field. It searched for the keyword 'hypospadias' in the three most popular databases (PubMed, Scopus and Web of Science). After the analysis of the publications, they were categorized into different domains.

show abstract

Protective effects of hydrogen rich saline solution on ventral penile mathieu type flap with penile tourniquet application in rats

Cited by 4 publications

References 30 publications

Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases

Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases

Protective Effects of Hydrogen-Rich Saline on Experimental Intestinal Volvulus in Rats

Current perspectives in hypospadias research: A scoping review of articles published in 2021 (Review)

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