Protective Effects of Sesamol and Its Related Compounds on Carbon Tetrachloride Induced Liver Injury in Rats

Neuropsychopharmacological effect of sesamol in unpredictable chronic mild stress model of depression: behavioral and biochemical evidences

“…It has been shown that sesamol inhibits several steps in the generation of neoplasia and mutagenesis (Kapadia et al 2002;Kaur and Saini 2000). Sesamol has been shown to possess antioxidant (Kanimozhi and Prasad 2009), neuroprotective (Hou et al 2006), hepatoprotective (Hsu et al 2006;Ohta et al 1994), anti-inflammatory (Chavali et al 2001;Hou et al 2006), chemopreventive (Prasad et al 2005b), and antiaging properties (Sharma and Kaur 2005). Because of its strong antioxidant, anti-inflammatory, and neuroprotective properties, we have evaluated sesamol against stress-induced depression in mice.…”

Radioprotective effect of sesamol on γ-radiation induced DNA damage, lipid peroxidation and antioxidants levels in cultured human lymphocytes

“…It is a phenolic derivative with a methylenedioxy group and like vitamin E is known to be an antioxidant (Uchida et al, 1996). Recent studies have shown that sesamol can act as a potent antioxidant (Suja et al, 2004) and possess chemopreventive, antimutagenic and antihepatotoxic properties (Kaur and Saini, 2000;Ohta et al, 1994;Kapadia et al, 2002). Very little work has been carried out on its role in the defense against radiation induced cellular damage.…”

Cytotoxic Characteristics of Two Isomeric Dimers Produced by Oxidation of Sesamol, an Antioxidant in Sesame Oil

“…From many basic studies, [5][6][7][8][9][10] the antioxidant effect of sesamol, a constituent of sesame oil, is beneficial for human health. Furthermore, the antioxidant property of sesamol seems to be utilized in the treatments of hepatic and renal injuries that are induced by oxidative stress.…”

“…3,4) This antioxidant is reported to exert many beneficial actions such as antimutagenic, chemopreventive, and antihepatoxic actions. [5][6][7][8][9][10] However, we previously determined some cytotoxic compounds produced by the oxidation of sesamol. 11,12) In this study, the cytotoxic characteristics of two isomeric dimers (dimer A and B of Fig.…”