Protective sensitivity changes of the motor cortex due to epileptiform experience of the visual cortex

Effects of second generation tetracyclines on penicillin-epilepsy-induced hippocampal neuronal loss and motor incoordination in rats

“…In this study, the seizures started after 2-4 min, a result consonant with those reported seizures after 2-3 min Horn et al, 1993). On the other hand, generalization of the seizures after 30 min and the observed symptoms (perioral movements, gnawing, ataxia, tail erection, circling, revolving and sudden jumps) are also in line with that reported in the mice (Dökmeci et al, 1994), except in the latter study the seizures started after 1 min.…”

“…In the PE model, synthesis and reuptake of GABA decreases at the penicillin application site (Avoli et al, 1982;Horn et al, 1993). On the other hand, PE increases glutamatergic activity (Avoli et al, 1982;El-Yamany and Horn, 2002), whereas excitatory amino acid inhibitors could abolish EEG spikes in the PE (Loeb et al, 1990).…”