Protein Synthesis, Bodily Renewal and the Sleep-Wake Cycle

Adám, K; Oswald, Ian

doi:10.1042/cs0650561

Cited by 151 publications

(69 citation statements)

References 59 publications

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“…Visual feedback for pedal frequency, power output and elapsed time were provided. All strength and/or endurance based exercise commenced at the same time of day (0900 h ± 1h) to avoid any diurnal performance or signalling variations 25 .…”

Section: Figure 1 About Herementioning

confidence: 99%

Signaling Responses After Varying Sequencing of Strength and Endurance Training in a Fed State

Jones

Walshe

Hamilton

et al. 2016

International Journal of Sports Physiology and Performance

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word count: 249 2 AbstractPurpose: The objective of this study was to compare anabolic signalling responses to differing sequences of concurrent strength and endurance training in a fed state.Methods: Eighteen resistance-trained males were randomly assigned to the following experimental conditions; i) strength training (ST), ii) strength followed by endurance training (ST-END) or iii) endurance followed by strength training (END-ST). Muscle tissue samples were taken from the vastus lateralis before each exercise protocol, upon cessation of exercise, and 1 h-post cessation of strength training. Tissue was analysed for total and phosphorylated (p-) signalling proteins linked to the mTOR and AMPK networks.Results: Strength training performance was similar between ST, ST-END and END-ST. pS6k1 was elevated from baseline 1 h post training in ST and ST-END (both p < 0.05). p-4E-BP1 was significantly lower than baseline post ST (p = 0.01), while 1 h post exercise in the ST-END condition p-4E-BP1 was significantly greater than post exercise (p = 0.04). p-ACC was elevated from baseline both post and 1 h post exercise (both p < 0.05) in the END-ST condition. AMPK, mTOR, p38, PKB, eEF2 responded similarly to the ST, ST-END and END-ST. Signalling responses to ST, ST-END and END were largely similar. As such it cannot be ascertained which sequence of concurrent strength and endurance training is most favourable in promoting anabolic signalling.Conclusions: These data indicate that in the case of the present study an acute bout of concurrent training of differing sequences elicited similar responses of the AMPK and mTOR networks.

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Section: Figure 1 About Herementioning

confidence: 99%

Signaling Responses After Varying Sequencing of Strength and Endurance Training in a Fed State

Jones

Walshe

Hamilton

et al. 2016

International Journal of Sports Physiology and Performance

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“…The restorative theory considers brain activity during sleep essential to restore body and mind [8,9]. As non restorative sleep is common in patients with organic sleep disorders, it has been considered a symptom of insomnia.…”

Section: Introductionmentioning

confidence: 99%

Sleep Disorders in Fibromyalgia Syndrome

Rizzi¹,

Cristiano²,

Frassanito³

et al. 2016

J Pain Relief

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“…Previous studies have found that higher energy expenditure during the day is associated with energy conservation and tissue restoration during sleep [11,12,13], whilst the exercise-induced increase in core body temperature may activate sleep-associated heat-loss mechanisms (see [13] for an overview). In addition, physical exercise has been shown to have a positive influence on longer sleep duration [14,15,16].…”

Section: Introductionmentioning

confidence: 99%

Impact of Physical Fitness and Daily Energy Expenditure on Sleep Efficiency in Young and Older Humans

Oudegeest-Sander¹,

Eijsvogels²,

Verheggen³

et al. 2012

Gerontology

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Background: Physical activity is known to influence sleep efficiency. Relatively little is known about the relationship between physical activity and sleep efficiency in young and older humans and the impact of exercise training on sleep efficiency in healthy older individuals. Objectives: To determine the relationship between physical fitness and daily energy expenditure with sleep efficiency in young and older subjects, and assess the effect of 12-month exercise training on sleep efficiency in healthy older participants. Methods: The relationship between physical fitness (maximal cycling test) and daily energy expenditure (accelerometry) with sleep efficiency (accelerometry) was examined cross-sectionally in 12 healthy young adults (27 ± 5 years) and 21 healthy older participants (69 ± 3 years). Subsequently, the effect of 12-month exercise training (n = 11) or control period (n = 10) on sleep efficiency in older participants was examined using a randomized controlled trial. Results: Daily energy expenditure and sleep efficiency did not differ between young and older subjects. A significant correlation was found between energy expenditure and sleep efficiency (r = 0.627, p = 0.029) in young adults, but not in older participants (r = –0.158, p = 0.49). Physical fitness did not correlate with sleep efficiency in either group. Exercise training significantly improved physical fitness (15.0%, p < 0.001), but failed to alter sleep characteristics such as sleep efficiency, sleep onset latency and awakenings. Conclusions: We found that young adults with higher daily energy expenditure have greater sleep efficiency, whilst this relationship is diminished with advanced age. In contrast, we found no correlation between physical fitness and sleep characteristics in healthy young or older participants, which may explain the lack of improvement in sleep characteristics in older participants with 12-month exercise training. Exercise training may be more successful in subjects with existing sleep disturbancesto improve sleep characteristics rather than in healthy older subjects.

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Protein Synthesis, Bodily Renewal and the Sleep-Wake Cycle

Cited by 151 publications

References 59 publications

Signaling Responses After Varying Sequencing of Strength and Endurance Training in a Fed State

Signaling Responses After Varying Sequencing of Strength and Endurance Training in a Fed State

Sleep Disorders in Fibromyalgia Syndrome

Impact of Physical Fitness and Daily Energy Expenditure on Sleep Efficiency in Young and Older Humans

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