Proteinuria in Chronic Kidney Disease and its Management

Ahmed, Sabahat; Laila, TR; Begum, Hameedunnisa; Moniruzzaman, Mohammad

doi:10.3329/medtoday.v25i1.16070

Cited by 5 publications

(10 citation statements)

References 28 publications

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“…For table (1), the knowledge of both study groups for the risks and side effects of taking nutritional supplements is shown. For control group, the results revealed that 30/30 (100%) was known the risks, whereas there are 0/30 (0%) was unaware the risks.…”

Section: Resultsmentioning

confidence: 99%

Changes in Blood Biochemical Parameters in Bodybuilders Using Supplements, Steroids and their Effect on the Kidneys in Iraq

Albakaa¹,

Khudhair²,

Al-Muhsen³

2020

ATMPH

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The enhanced body activities after taking the nutritional addendum by athletes were observed via fluctuation in the clinical biomarkers. There are some previous evidences recorded that the nutritional supplements have a benefit and side influences, hence current paper was aimed to determine the potential influences of nutritional support compounds on biochemical parameters and kidneys damage among bodybuilders people. Two subjects of sportsmen bodybuilders; first group not take the nutritional supplements (control group), whereas the second group take the nutritional supplements (users group) were included within current study and screened for their serological level of creatinine, urea, total protein and albumin with measuring urine total protein and pH. The results showed that the mean titer of serum creatinine, serum albumin and urine total protein were significantly higher among users group compared to control group, whereas the level of serum urea, serum total protein and urine pH revealed non-significant different between both groups. For subjects aware to the risks and side effects of taking the nutritional supplements, the users group exhibited a significant higher frequency % of unaware to the risks in comparison to control group. In denouement, there is prodromal defect in the kidneys of the nutritional supplements consumers, confirmed by serum creatinine, serum albumin and urine total protein increase. Many of nutritional supplements users not have enough information about the consequences and side effects of the decompounds hence exercising related with abuse of it without consulting a dietitian may be hazardous.

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Section: Resultsmentioning

confidence: 99%

Changes in Blood Biochemical Parameters in Bodybuilders Using Supplements, Steroids and their Effect on the Kidneys in Iraq

Albakaa¹,

Khudhair²,

Al-Muhsen³

2020

ATMPH

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“…According to the 2012 data, the total expenses for medical treatment of patients with end‐stage renal failure is similar to those of all cancer patients, and the expenses of medical treatment per patient are the highest among all diseases . Therefore, in patients with a high potential risk of kidney function, it is essential to periodically monitor the kidney function and to treat the progressive slowing down of the renal function as early as possible . An increased excretion of urinary protein, especially albumin, is an early finding of renal damage, and measurement of urinary albumin has been a useful marker for diagnosis and follow‐up of renal failure with estimated glomerular filtration rate .…”

Section: Introductionmentioning

confidence: 99%

“…The urine albumin/creatinine ratio (ACR) test is also used to screen patients with chronic diseases that put them at an increased risk of developing kidney disease. ACR is a surrogate marker of urine albuminuria . A quantitative evaluation of moderately increased albuminuria requires the use of expensive biochemical instruments and reagents, making it difficult to perform in small or medium‐sized clinics.…”

Section: Introductionmentioning

confidence: 99%

“…function, it is essential to periodically monitor the kidney function and to treat the progressive slowing down of the renal function as early as possible. 1,[4][5][6][7][8] An increased excretion of urinary protein, especially albumin, is an early finding of renal damage, and measurement of urinary albumin has been a useful marker for diagnosis and follow-up of renal failure with estimated glomerular filtration rate. 4,9 The urine albumin/ creatinine ratio (ACR) test is also used to screen patients with chronic diseases that put them at an increased risk of developing kidney disease.…”

mentioning

confidence: 99%

“…ACR is a surrogate marker of urine albuminuria. 6 A quantitative evaluation of moderately increased albuminuria requires the use of expensive biochemical instruments and reagents, making it difficult to perform in small or medium-sized clinics. Even if an evaluation has been performed, it needs to be sent to a central clinical laboratory, so it is difficult to conduct an early diagnosis and frequent monitoring.…”

mentioning

confidence: 99%

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Evaluation of the URiSCAN 2 ACR Strip to estimate the urine albumin/creatinine ratios

Lim

Lee

et al. 2017

Clinical Laboratory Analysis

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Combination of Tamsulosin with Potassium Citrate Effect on Serum Oxidoreductases in Patients with Nephrolithiasis

Zainulabdeen¹,

Suhail²,

Saifull³

2018

Orient. J. Chem

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This study was designed to prove the probable effect of oral treatment (combination of tamsulosin with potassium citrate) on serum xanthine oxidoreductases and oxidative stress levels for patients with nephrolithiasis. A total of 55 newly diagnosed nephrolithiasis patients (P1 group) were involved in this study matched with 30 apparently healthy volunteers (C group); 22 of the patients (P2 group) were followed after treatment. Blood urea, creatinine, uric acid, total serum protein (TSP), and albumin were measured by using Abbott c400 analyzer. Colorimetric methods were used to detect total antioxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), xanthine oxidoreductases enzymes (xanthine oxidase (XO) and xanthine dehydrogenase (XDH)) and other biochemical parameters. One-way ANOVA test was used for data analysis. For P1 group in comparison to that of C and P2 groups, the observed results were as follows: significant increases were observed in serum urea, creatinine, MDA, TOS, TAS, OSI, XO, and UA, p=0.007, p=0.001, p=0.000, p=0.000, p=0.000, p=0.002, p=0.039 respectively, while significant decreases were indicated XDH, TSP, and albumin, p=0.000, p=0.001, p=0.001 respectively. Meanwhile, the measured parameters were exhibited a good alteration after treatment (TOS and TAS were significantly decreased, while TSP and albumin were slightly increased). The present study suggests that the used treatment success in balancing the oxidative stress of nephrolithiasis patients by decreasing the oxidants and increasing the antioxidant parameters leading to prevent the renal damage.

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Proteinuria in Chronic Kidney Disease and its Management

Abstract: Abstract

Cited by 5 publications

References 28 publications

Changes in Blood Biochemical Parameters in Bodybuilders Using Supplements, Steroids and their Effect on the Kidneys in Iraq

Changes in Blood Biochemical Parameters in Bodybuilders Using Supplements, Steroids and their Effect on the Kidneys in Iraq

Evaluation of the URiSCAN 2 ACR Strip to estimate the urine albumin/creatinine ratios

Combination of Tamsulosin with Potassium Citrate Effect on Serum Oxidoreductases in Patients with Nephrolithiasis

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