Protocol for Functional Assessment of Adults and Older Adults after Hospitalization for COVID-19

Godoy, Caroline Gil de; Silva, Érika Christina Gouveia e; Oliveira, Danielle Brancolini de; Gambeta, Amislaine Cristina; Silva, Elizabeth Mendes da; Campos, Camila Machado de; Schmitt, Ana Carolina Basso; Carvalho, Celso; Fu, Carolina; Tanaka, Clarice; Nakagawa, Naomi Kondo; Toufen, Carlos; Carvalho, Carlos Roberto Ribeiro de; Pompeu, José Eduardo

doi:10.6061/clinics/2021/e3030

Cited by 9 publications

(5 citation statements)

References 28 publications

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“… 31 This syndrome can negatively influence the quality of life of the individual, and long-term follow-up studies on persistent symptoms in patients after hospital discharge following COVID-19 are considered fundamental. 32 In addition, hospitalization can lead to disabilities due to underlying disease and low levels of mobility, even with adequate treatment. This condition can cause serious long-term consequences, including an increased risk of hospital readmission, mortality, and symptoms possibly lasting for months after hospital discharge.…”

Section: Discussionmentioning

confidence: 99%

Ambulation capacity, age, immunosuppression, and mechanical ventilation are risk factors of in-hospital death in severe COVID-19: a cohort study

Silva

Schmitt

Godoy

et al. 2022

Clinics

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Section: Discussionmentioning

confidence: 99%

Ambulation capacity, age, immunosuppression, and mechanical ventilation are risk factors of in-hospital death in severe COVID-19: a cohort study

Silva

Schmitt

Godoy

et al. 2022

Clinics

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“…Finally, only a few studies with a small number of participants have evaluated the impairment of ambulation in adults and older adults hospitalized with COVID-19 [32,33,45]. Therefore, post-hospital follow-up is necessary to investigate possible people suffering from Post COVID Syndrome [46,47]. Our study, despite the fact that it can only show associations, contributes to filling this gap in the literature and seeks to elucidate the functional impact of COVID-19 on older adults, helping to devise new interventions for COVID-19 prevention and rehabilitation related to this population.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors for the Impairment of Ambulation in Older People Hospitalized with COVID-19: A Retrospective Cohort Study

Silva,

Schmitt,

de Godoy

et al. 2023

IJERPH

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(1) Background: Some older people hospitalized with COVID-19 have experienced reduced ambulation capacity. However, the prevalence of the impairment of ambulation capacity still needs to be established. Objective: To estimate the prevalence of, and identify the risk factors associated with, the impairment of ambulation capacity at the point of hospital discharge for older people with COVID-19. (2) Methods: A retrospective cohort study. Included are those with an age > 60 years, of either sex, hospitalized due to COVID-19. Clinical data was collected from patients’ medical records. Ambulation capacity prior to COVID-19 infection was assessed through the patients’ reports from their relatives. Multiple logistic regressions were performed to identify the risk factors associated with the impairment of ambulation at hospital discharge. (3) Results: Data for 429 older people hospitalized with COVID-19 were randomly collected from the medical records. Among the 56.4% who were discharged, 57.9% had reduced ambulation capacity. Factors associated with reduced ambulation capacity at discharge were a hospital stay longer than 20 days (Odds Ratio (OR): 3.5) and dependent ambulation capacity prior to COVID-19 (Odds Ratio (OR): 11.3). (4) Conclusion: More than half of the older people who survived following hospitalization due to COVID-19 had reduced ambulation capacity at hospital discharge. Impaired ambulation prior to the infection and a longer hospital stay were risks factors for reduced ambulation capacity.

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“…We conducted a 1-year follow-up among patients who were admitted to referral hospitals for SARS-CoV-2 infection between April 2020 to April 2021. (10) After discharge from hospital, patients were evaluated at two points: 1 and 12 months after hospital discharge. The study was approved by the Ethics Committee for the Analysis of Research Projects of the HCFMUSP (approval number: 31942020.0.0000.0068).…”

Section: Methodsmentioning

confidence: 99%

Neuroleptics used in critical COVID associated with moderate- severe dyspnea after hospital discharge

Toufen

Almeida

Pompeo

et al. 2023

Preprint

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Background Dyspnea is a central symptom in patients with long-term COVID, both because of frequency and clinical impact. The effect of the drugs most used in critically ill patients on long-term dyspnea is not known. The aim of this study was to assess the risk factors and impacts associated with moderate to severe dyspnea in COVID-19 survivors.Methods Patients admitted to a university hospital between April 2020 and April 2021 were evaluated. It was collected data associated with clinical preconditions, hospital and ICU stay, use of corticosteroids, neuroleptics, neuromuscular blockers, midazolam, fentanyl, and noradrenaline. After hospital discharge, patients were evaluated in 1 and 12 months. In the evaluations, dyspnea, frailty, quality of life, functional capacity, anxiety and depression were measured. Descriptive statistics in the form of frequencies and percentages and a logistic regression analysis were done to assess the factors associated with moderate to severe dyspnea after 1 and 12 months from hospital discharge and statistical significance was set at P < 0.05.Results 100 patients were prospectively included, with 100 patients underwent the 1-month evaluation and 63 underwent the 12-month evaluation. Presented with limiting dyspnea (defined as mMRC score > 1) 56.6% of patients after 1 month and 33.9% after 12 months. Independent factors associated with limiting dyspnea 1 month after hospital discharge were the total dose of neuroleptics used during hospitalization and the presence of comorbidities prior to hospitalization. Use of corticosteroids, neuromuscular blockers, midazolam, fentanyl, and noradrenaline were not associated with limiting dyspnea. Dyspnea 1 month after hospital discharge was an independent risk factor for the occurrence of limiting dyspnea 12 months after discharge. Patients with limiting dyspnea 12 months after discharge showed more depression, anxiety and frailty, and had lower quality of life and functionality.Conclusions Patients with long-term severe COVID have a high frequency of limiting dyspnea. The total dose of neuroleptics used in hospital and the presence of comorbidities were independently related to the presence of limiting dyspnea after hospital discharge. After 12 months, patients who maintained limiting dyspnea presented in high frequency with other physical and mental dysfunction that should be evaluated and treated in the aim of reducing the burden of disabilities.

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Protocol for Functional Assessment of Adults and Older Adults after Hospitalization for COVID-19

Cited by 9 publications

References 28 publications

Ambulation capacity, age, immunosuppression, and mechanical ventilation are risk factors of in-hospital death in severe COVID-19: a cohort study

Ambulation capacity, age, immunosuppression, and mechanical ventilation are risk factors of in-hospital death in severe COVID-19: a cohort study

Risk Factors for the Impairment of Ambulation in Older People Hospitalized with COVID-19: A Retrospective Cohort Study

Neuroleptics used in critical COVID associated with moderate- severe dyspnea after hospital discharge

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