2020
DOI: 10.1136/bmjopen-2020-039587
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Protocol for Project Fizzyo, an analytic longitudinal observational cohort study of physiotherapy for children and young people with cystic fibrosis, with interrupted time-series design

Abstract: IntroductionDaily physiotherapy is believed to mitigate the progression of cystic fibrosis (CF) lung disease. However, physiotherapy airway clearance techniques (ACTs) are burdensome and the evidence guiding practice remains weak. This paper describes the protocol for Project Fizzyo, which uses innovative technology and analysis methods to remotely capture longitudinal daily data from physiotherapy treatments to measure adherence and prospectively evaluate associations with clinical outcomes.Methods and analys… Show more

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Cited by 18 publications
(19 citation statements)
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“…Variance analysis (analysis of variance) and significance tests such as permutations were also used. Further data analyses were conducted in a data-driven manner [223] with artificial intelligence, such as k-means [176] or unsupervised cluster analysis [172], recursive feature elimination technique [170], rotation random forest classifier [130], and supervised machine learning algorithms using logistic regression, decision tree, and random forest [215].…”
Section: Wearable Characteristicsmentioning
confidence: 99%
“…Variance analysis (analysis of variance) and significance tests such as permutations were also used. Further data analyses were conducted in a data-driven manner [223] with artificial intelligence, such as k-means [176] or unsupervised cluster analysis [172], recursive feature elimination technique [170], rotation random forest classifier [130], and supervised machine learning algorithms using logistic regression, decision tree, and random forest [215].…”
Section: Wearable Characteristicsmentioning
confidence: 99%
“…Essa análise permitiu identificar os perfis distintos de indivíduos com a patologia e qual o tipo de tratamento pode ser de melhor aplicação, a depender das suas variáveis sociodemográficas. (6) Outro, de forma online, faz o monitoramento de crianças para identificar possíveis padrões de comportamento que justifiquem a obesidade infantil. Contudo, com o fechamento das escolas na pandemia, o número de crianças ficou restrito.…”
Section: Data Science Inunclassified
“…15 A growing number of platforms such as projects Fizzyo and CFHealthHub which remotely captures and analyzes adherence data and clinical outcomes such as airway clearance and nebulizer usage will in the future support intervention studies to improve the health care of pwCF. 16,17 A more recent retrospective multicenter observational study of 318 adults with CF used data capture of nebulizer usage through the CFHealthHub platform. 18 The low realworld adherence to therapy was confirmed, with half of the study population having objective adherence of less than one in three.…”
Section: Registriesmentioning
confidence: 99%
“…A growing number of platforms such as projects Fizzyo and CFHealthHub which remotely captures and analyzes adherence data and clinical outcomes such as airway clearance and nebulizer usage will in the future support intervention studies to improve the health care of pwCF. 16 17…”
Section: Adherence Monitoring Platformsmentioning
confidence: 99%