Protracted form of Encephalitis with Good Outcome

Abstract

ObjectiveTo present four patients seen over a five‐year period who developed severe protracted encephalitic illnesses but whose outcomes were favourable. Clinical featuresOf the four patients, aged 18, 22, 34 and 19, three presented with acute psychosis, and all had a prolonged clinical course requiring intensive care management. One patient had residual generalised seizures and the other three recovered fully. No infective or toxic agent could be identified but viral encephalitis was considered most likely. OutcomeDespite the protracted courses, the outcomes were favourable. This is in contrast to the generally poor outcomes in encephalitis caused by established infective agents such as herpes simplex type 1. ConclusionsWhen the aetiology and hence the natural history of the encephalitis is unknown, long‐term intensive support is appropriate.

Acute and transient psychosis: A paradigmatic approach

“…Acute schizophrenic episode could be considered to be a culture-related syndrome,[ 86 ] whereas Fisch[ 87 ] described psychosis precipitated by marriage as a culture-bound syndrome. Acute Psychotic manifestations in patients suffering from organic brain infections have been reported by Frasca et al ,[ 88 ] Jarvis et al ,[ 89 ] Klein et al [ 90 ] and Srikanth et al . [ 91 ]…”

Treatment of Viral Encephalitis Organic Personality Disorder and Autistic Features with Propranolol: A Case Report

“…Although the neuroimaging was consistent with characteristics of herpes encephalitis, neither cerehrospinal fluid titers nor the brain biopsy revealed evidence of HSV (20)(21)(22)(23)(24)(25)(26). Other sporadic viral infections may be considered, such as Epstein-Barr virus and mumps, although these are rare (25)(26).…”

“…Other sporadic viral infections may be considered, such as Epstein-Barr virus and mumps, although these are rare (25)(26). Most of the arboviruses causing encephalitis are usually acquired in late summer or early fall (27).…”

Protracted mumps encephalitis with good outcome

“…Our report highlights that when the natural history of the encephalitis is uncertain, long-term intensive support is indicated. 10 INTRODUCTION Medullomyoblastoma (MMB) was first described by Marinesco and Goldstein in 1935 and is considered a primitive neuroectodermal tumor (PNET) having a component of striated and smooth muscle and is thought to be a variant of malignant teratoma or a teratoid tumor with poor outcome despite surgery and radiotherapy. [1][2][3][4] Less than 40 cases have been reported in the literature to date with maximum survival being 3 to 4 years, even after surgical excision and radiotherapy.…”