Provocation-challenge studies in shrimp-sensitive individuals

The IgE and IgG antibody responses to aerosols of Nephrops norvegicus (prawn) antigens: the association with clinical hypersensitivity and with cigarette smoking

“…As with ingested seafood allergy [4,5], where IgE antibody had a predictive value of 87% for clinical sensitivity (a reaction to ingested shrimp) [15], this IgE antibody was found to be the most useful serological discriminator between symptomatic and asymptomatic subjects. However, better discrimination between the two symptom groups could be achieved by considering other diagnostic data in conjunction with anti-prawn IgE, notably total IgE and serum cotinine.…”

Key issues for the assessment of the allergenic potential of genetically modified foods: breakout group reports.

“…NOEL was 4 g shrimp equivalents/207 g ice cream. No effects were elicited in this cohort with 1 g shrimp equivalents/207 g ice cream (Daul et al 1988). c Results from infants exposed to these allergens in mother's breast milk.…”

Characterization of Seafood Proteins Causing Allergic Diseases

“…Shrimp allergy is estimated to be about 2% of the general population (Besler et al, 2001;Lopata et al, 2010). The threshold doses for shrimp allergic individual were evaluated to be 16g (Daul et al, 1988) and for fish ranging from 5-600 mg (Taylor et al, 2002) using the double-blind placebo controlled food challenges (DBPCFC). Cod fish allergen, the first reported allergen, was also evaluated by RAST to study the physico-chemical properties and the cross-reactivity with other fish species (Aas & Elsayed, 1975;Aas & Lundkvist, 1973;Aukrust et al, 1978).…”

“…The RAST technique was used as a diagnosis method, where the positive skin test patient sera were evaluated using a crude extract of the potential allergenic seafood, such as in crustaceans, prawn, shrimp, crawfish, and lobster (Daul et al, 1988;Halmepuro et al, 1987;Nagano et al, 1984). This technique was used to study the cross-reactivity between the oyster and crustacean (Lehrer & McCants, 1987) and caddis fly with arthropoda and mollusca (Koshte et al, 1989), which indicated to the non-specificity of RAST to be a diagnostic assay.…”