Proxies of cognitive reserve and their effects on neuropsychological performance in patients with mild cognitive impairment

Liu, Yuanyuan; Cai, Zenglin; Xue, Shouru; Zhou, Xinyu; Wu, Fenfang

doi:10.1016/j.jocn.2012.04.020

Cited by 35 publications

(43 citation statements)

References 16 publications

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“…The observations obtained in this study on a larger sample (N = 337) provide preliminary normative data for the study of healthy aging, while data relating to response to task difficulty may also further inform future analyses relating to cognitive reserve through examination of inter-individual disparities in the recruitment of neural networks (Scarmeas and Stern 2003;Barnett et al 2006;Stern 2009;Murray et al 2011;Jones et al 2011;Liu et al 2013).…”

Section: 1increased Task Load Effectmentioning

confidence: 75%

Working memory activation of neural networks in the elderly as a function of information processing phase and task complexity

Charroud

Steffener

Bars

et al. 2015

Neurobiology of Learning and Memory

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Section: 1increased Task Load Effectmentioning

confidence: 75%

Working memory activation of neural networks in the elderly as a function of information processing phase and task complexity

Charroud

Steffener

Bars

et al. 2015

Neurobiology of Learning and Memory

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“…However, these CR proxies also correlate with abstract and reasoning tasks that are initially less influenced by education [19], [21]. Zahodne et al [67], using a large sample (1014 participants), demonstrated that education influenced cognitive performance.…”

Section: Discussionmentioning

confidence: 99%

Estimating Cognitive Reserve in Healthy Adults Using the Cognitive Reserve Scale

2014

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The concept of cognitive reserve emerged from observed disparities between brain pathology and clinical symptoms. It may explain better neuropsychological performance in healthy individuals. The objectives of this study were to measure reserve in healthy subjects using a new Cognitive Reserve Scale (CRS), analyze the internal consistency of the CRS, and analyze validity evidence. A total of 117 healthy individuals were divided into two groups: 87 adults (aged 18–64 years) and 30 elderly adults (≥65 years). All subjects completed the CRS and a comprehensive neuropsychological battery. The internal consistency of the scale was satisfactory (α = 0.77). No significant differences were observed between genders (t = 0.51, p = 0.611), and age was corrected by averaging the CRS score. The study of validity evidence showed that education affected the CRS (t = −2.98, p = 0.004, partial h2 = 0.07) and there was no significant relationship between the CRS and IQ (r = 0.09, p = 0.33). Occupational attainment and the CRS were not related (F2,116 = 0.11, p = 0.898). In line with previous studies on reserve, heterogeneity was observed in the analyses of relationships between the CRS and cognitive performance. There were significant relationships between CRS score and the Verbal Learning Spanish–Complutense Test last trial (r = 0.24, p = 0.009), sum (r = 0.32, p = 0.000), short-term (r = 0.29, p = 0.002) and long-term memory (r = 0.22, p = 0.018), Matrix Reasoning subtest (r = 0.20, p = 0.027) and Block Design subtest (r = 0.20, p = 0.029). No other neuropsychological variables correlated with the CRS (p>0.05). The CRS is a reliable instrument that reflects the frequency of participation in brain-stimulating activities across the lifetime. The associations between the CRS and education and neuropsychological performance support validity evidence.

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“…Finally, the sample was well educated. Given that education has been related to cognitive reserve (Liu et al, 2013), even greater differences in cognition among aging BPD patients may be detected in studies with less educated participants.…”

Section: Discussionmentioning

confidence: 99%

The double burden of age and disease on cognition and quality of life in bipolar disorder

Weisenbach

Marshall

Weldon

et al. 2014

Int J Geriatr Psychiatry

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Proxies of cognitive reserve and their effects on neuropsychological performance in patients with mild cognitive impairment

Cited by 35 publications

References 16 publications

Working memory activation of neural networks in the elderly as a function of information processing phase and task complexity

Working memory activation of neural networks in the elderly as a function of information processing phase and task complexity

Estimating Cognitive Reserve in Healthy Adults Using the Cognitive Reserve Scale

The double burden of age and disease on cognition and quality of life in bipolar disorder

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