Prunus lusitanica L. Fruits as a Novel Source of Bioactive Compounds with Antioxidant Potential: Exploring the Unknown

Abraão, Ana S.; Fernandes, Nelson Ferreira; Silva, Amélia M.; Domínguez‐Perles, Raúl; Barros, Ana

doi:10.3390/antiox11091738

Cited by 11 publications

(12 citation statements)

References 154 publications

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“…The [M-H] − ion at m/z 337 amu was detected, providing fragmentation base peaks at m/z 163 amu. This fragmentation yielded the MS2 base peak correspondent to the [p-coumaric acid-H] − fragment, characteristic of 3-p-coumaroylquinic acid, which is in agreement with previous reports [38].…”

Section: Quantitative Phenolic Profile Via Hplc-dad-esi-ms/mssupporting

confidence: 92%

“…Peak 5 demonstrated a deprotonated molecular ion at m/z 609 amu, resulting in a loss of 301 amu, corresponding to the loss of a hexose moiety, as previously reported [38].…”

Section: Quantitative Phenolic Profile Via Hplc-dad-esi-ms/mssupporting

confidence: 80%

“…Compound 1 showed a deprotonated molecular ion at an arbitrary mass unit (amu) of m/z 353, exhibiting a base peak at m/z 191, corresponding to deprotonated quinic acid, [quinic acid-H] − , and another characteristic ion at m/z 179 amu, [caffeic acid-H] − , in MS2 [38]. This allowed for its identification as 3-O-caffeoylquinic acid, which agrees with the phenolic alcohol profile described in this by-product [39].…”

Section: Quantitative Phenolic Profile Via Hplc-dad-esi-ms/msmentioning

confidence: 99%

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Optimization of the Extraction Methodology of Grape Pomace Polyphenols for Food Applications

et al. 2023

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This study aims to take advantage of the wine industry by-products and extract bioactive compounds from grape pomace by applying methodologies susceptible to be integrated easily into industrial workflows because of the association with standard instrumentation and facilities, while the main factors affecting the efficiency of the process have been optimized. The sampling consisted of two grape varieties: ‘Touriga Nacional’ and ‘Sousão’. A response surface methodology (RSM) method was used to optimize the extraction conditions based on three independent variables according to the chemical characteristics and stability/lability traits associated with polyphenols; the main bioactive phytochemical in grape pomace: solvent (50%, 70%, and 90% ethanol); temperature (20 °C, 40 °C, and 60 °C); and pH (0.5% HCl, 2% HCl, and 3.5% HCl). The phytochemical profile, as well as the radical scavenging and reducing powers were determined on 27 different samples. The highest yield and antioxidant activity corresponded to extracts obtained at 60 °C using 3.5% HCl and 70% ethanol. The values for total phenols and flavonoids were 44.93 mg of gallic acid equivalents (GAE) and 22.95 mg of catechins equivalents (CE) per gram, respectively. Concerning the evaluation of antioxidant capacity using various assays such as ABTS, DPPH, and FRAP, the results obtained were 0.30, 0.43, and 0.36 mmol of Trolox equivalent antioxidant capacity (TEAC) per gram, correspondingly. The analysis of the extract obtained with the best extraction performance using these parameters via High-Performance Liquid Chromatography–Mass Spectrometry has been also performed, allowing us to identify fourteen (14) compounds, including phenolic acids (n = 3), flavonols (n = 7), and anthocyanins (n = 4). As a result of this process, the best conditions for the production of a natural and environmentally friendly dye, not only avoiding waste but also reusing these by-products, were achieved.

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Section: Quantitative Phenolic Profile Via Hplc-dad-esi-ms/mssupporting

confidence: 92%

“…Peak 5 demonstrated a deprotonated molecular ion at m/z 609 amu, resulting in a loss of 301 amu, corresponding to the loss of a hexose moiety, as previously reported [38].…”

Section: Quantitative Phenolic Profile Via Hplc-dad-esi-ms/mssupporting

confidence: 80%

Section: Quantitative Phenolic Profile Via Hplc-dad-esi-ms/msmentioning

confidence: 99%

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Optimization of the Extraction Methodology of Grape Pomace Polyphenols for Food Applications

et al. 2023

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“…The schematic representation of the methodologies employed in the present study is illustrated in Figure 9 . The extraction of phenolic compounds was carried out according to Abraão et al [ 59 ] with some modifications. To perform the extracts, the stems, whole pomace, and seeds were dried in an oven (Memmert, Schwabach, Germany) for 72 h at 40 °C.…”

Section: Methodsmentioning

confidence: 99%

Exploring the Antioxidant Potential of Phenolic Compounds from Winery By-Products by Hydroethanolic Extraction

Costa,

Domínguez-Perles,

Abraão

et al. 2023

Molecules

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The residues generated in the wine industry (pomace, stems, seeds, wine lees, and grapevine shoots) are a potential source of bioactive compounds that can be used in other industries despite being sometimes underestimated. Different extraction methods using various solvents and extraction conditions are currently being investigated. Due to its natural occurrence in wines, safe behavior, and low toxicity when compared to other organic solvents, ethanol is used as an extracting agent. The aim of this study was to identify the winery by-product from the Região Demarcada do Douro and its corresponding extraction solvents that yields the most favorable results in (poly)phenols content and antioxidant capacity. To achieve this, five different ratios of ethanol: water, namely 0:100, 25:75, 50:50, 75:25, and 100:0 (v/v), for extracting the phenolic compounds were employed. Afterwards, the determination of total phenolic content (TPC), ortho-diphenols content (ODC), and flavonoid content (FC) as well as the antioxidant capacity of the obtained extracts using three different methods was performed. Since the best results of the spectrophotometric assays were obtained mostly with hydroethanolic extracts of stems (50:50, v/v), identification by HPLC-DAD has carried out. It was possible to conclude that the Tinta Roriz variety displayed the highest number of identified (poly)phenols.

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“…Ferric-reducing antioxidant power (FRAP) assay was used to characterize the antioxidant capacity of the extracted EOs as reported by Abraão et al . [ 10 ] To measure the FRAP, EOs (100 μL) were placed in a test tube, followed by 3 mL of FRAP working solution (composed of 1 mL of TPTZ (2, 4, 6-tripyridyl-S-triazine, 10 mM dissolved in 40 mM HCl), 1 mL of FeCl3 (20 mM in water), and 10 mL of acetate buffer (300 mM, pH – 3.6). The mixture was incubated at 37°C, protected from light, for 30 min.…”

Section: Methodsmentioning

confidence: 99%

Investigations of chemical compositions and antioxidative potential of essential oils isolated from the leaves of two Garcinia species

Kokilananthan¹,

Bulugahapitiya²,

Manawadu³

et al. 2023

Journal of Advanced Pharmaceutical Technology &Amp; Research

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Garcinia quaesita and Garcinia zeylanica are Sri Lankan endemic plants with significant therapeutic potential and numerous health-care applications. Despite this, there are no adequate literatures reported on the chemical compositions (CCs) and antioxidative potential (AP) of leaves' essential oils (EOs). The purpose of this study was to extract EOs from the leaves and investigate the CCs and AP of the extracted EOs. The hydro-distillation technique was used to extract the EOs, and the CCs of the EOs were identified through gas chromatography–mass spectrometry analysis. Only those compounds that had a matching value of more than 90% were taken into consideration, and the AP of the extracted EOs was determined using the ferric-reducing antioxidant power (FRAP) assay. Hydro-distillation process yielded EOs in the same quantity, 0.12% (v/w) on a fresh weight basis for two varieties. About 33 CCs that were found in the extracted EOs were mainly sesquiterpenes. The most prevalent substances in the EOs were copaene (19.39%), caryophyllene (12.94%), alloaromadendrene (12.12%), α-humulene (11.24%), and α-cubebene (9.38%). It is interesting to note that copaene and alloaromadendrene were only found in G. quaesita, whereas α-cubebene was only found in G. zeylanica. Caryophyllene and α-humulene were identified in both EOs at different concentrations. The EO from G. quaesita showed high AP, presenting FRAP values 274.74 ± 1.32 μL Trolox Eq/L. This study is recognized as being the first to examine the CCs and AP of EOs, and the results may inspire the creation of new uses and high-value leaf products.

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Prunus lusitanica L. Fruits as a Novel Source of Bioactive Compounds with Antioxidant Potential: Exploring the Unknown

Cited by 11 publications

References 154 publications

Optimization of the Extraction Methodology of Grape Pomace Polyphenols for Food Applications

Optimization of the Extraction Methodology of Grape Pomace Polyphenols for Food Applications

Exploring the Antioxidant Potential of Phenolic Compounds from Winery By-Products by Hydroethanolic Extraction

Investigations of chemical compositions and antioxidative potential of essential oils isolated from the leaves of two Garcinia species

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