Ps 11-56 Efficacy of Combination Therapy Using Nebivalol and Trimetazidine in Hypertensive Patients With Metabolic Syndrome and Stable Angina

Usarov, Muzaffar; Mamatkulov, Xasan; Uzokov, Jamol; Hojiev, Sarvar; Yakhshilikov, Davron; Dadaev, Sarvar

doi:10.1097/01.hjh.0000500888.34489.96

Cited by 6 publications

(7 citation statements)

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“…The degree of platelet aggregation in patients without MS and AH was lower than in patients with these comorbid conditions [39]. The rate of platelet aggregation was also higher in patients with MS and AH [40]. The time of aggregation, as well as the indicator of the presence of disaggregation, were lower among patients without MS and AH.…”

Section: Resultsmentioning

confidence: 81%

Modern aspects of the application of antiplatelet and hypolipidemic therapy in ischemic heart disease after coronary artery stenting

Saydalievich¹

2021

GSC Biol. and Pharm. Sci.

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Section: Resultsmentioning

confidence: 81%

Modern aspects of the application of antiplatelet and hypolipidemic therapy in ischemic heart disease after coronary artery stenting

Saydalievich¹

2021

GSC Biol. and Pharm. Sci.

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“…At the same time, the non-oxidative way of consuming this carbohydrate is disturbed to a greater extent -glycogen synthesis, which is a result of the interaction of genetic (defect insulin receptors) and external factors, especially the formation of androgenic obesity and a decrease in blood volume in the capillaries of skeletal muscle as a result of their vasoconstriction, and this affects by increasing the diffusion pathway of glucose to the cells [18]. Target organs of hypertension in people with obesity are affected much earlier, and their changes are much more pronounced than in patients with hypertension without obesity [19]. Scientists have proven that IR and concomitant hyperinsulinemia trigger a number of pathological reactions that are closely associated with endothelial dysfunction and form a vicious circle leading to metabolic diseases [20].…”

Section: Pathogenetic Mechanisms Of Development Of Msmentioning

confidence: 99%

Contemporary View on Etiopathogenesis of Metabolic Syndrome

M.G¹

2019

SARJBAB

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Metabolic syndrome (MS) is a cluster of several risk factors such as abdominal obesity, hypertension, dyslipidemia, insulin resistance and considered risk for the development of the type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Knowing contemporary aspects of the development of this disease allows understanding underlining mechanisms of the MS. This review summarizes modern concepts of the metabolic syndrome and its etiology, pathogenesis and biochemical mechanisms of the development of the metabolic disease.

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“…Throughout pregnancy, the content of progesterone is maintained at a high level, a decrease in its concentration occurs towards the end of pregnancy, when the level of estrogen sharply increases [7]. From the very beginning of pregnancy and before childbirth, β-adrenoreactivity increases and α-adrenergic reactivity decreases, which is a necessary condition for reducing the contractile activity of the myometrium in order to carry a fetus [8]. The density of β-adrenergic receptors under the action of progesterone in the myometrium increases.…”

Section: Introductionmentioning

confidence: 99%