Pseudomonas septicemia; Necrotizing bowel lesions (NEC) and skin lesions in a 5-mo-old child

Multiple Opportunistic Pathogens, but Not Pre-existing Inflammation, May Be Associated with Necrotizing Enterocolitis

“…The current study did identify four opportunistic pathogens, Corynebacterium striatum [17], Morganella morganii [18], Pseudomans aeruginosa [19], and Corynebacterium amycolatum [20] in NEC samples. Further, all NEC infants had at least two opportunistic pathogens, whereas only one control infant had more than one of these organisms.…”

Community acquired fulminant Pseudomonas infection of the gastrointestinal tract in previously healthy infants

“…Including the three patients in our present series, 12 of the 16 reported cases (75%) presented initially with diarrhoea and pyrexia which were indistinguishable from ordinary gastroenteritis. [6,7,9,12–15] This makes an early diagnosis particularly difficult and has often led to significant delay in the institution of appropriate treatment, which in turn has translated into higher rates of morbidity and even mortality. Of note, ecthyma gangrenosum was present in 10 of the 16 (62.5%) patients, although it was often not recognised initially due to its rarity and hence unfamiliarity to the medical staff, and the correct diagnosis was made only after a substantial lapse of time.…”

Necrotizing bowel lesions complicated byPseudomonas septicaemia in previously healthy infants

“…Four cases were described with ages ranging from 2 days to 14 weeks in whom Pseudomonas aeruginosa was isolated from the blood, peritoneum, stool or vermiform appendix. There is, however, only one case report [4] of NBL with Pseudomonas septicaemia in previously well infants beyond the newborn stage. That infant also died.…”