2020
DOI: 10.1093/jas/skaa278.656
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PSII-36 The application of busulfan to inhibit the spermatogenesis in quail testis

Abstract: The use of testicular stem cells (spermatogonia) is of most interest for obtaining individuals with predetermined traits and genome genetic modification and for conservation of poultry gene pool. A significant population of mature donor germ cells (sperm) is formed upon successful spermatogonia cells transplantation into the testes of male recipients. Obtained sperm can be used to produce offspring with the desired traits. A key step in this technology is the removal of own spermatogenic cells (inhibition of s… Show more

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