In this paper, we investigate the transceiver design schemes for the full-duplex (FD) multiple-input multiple-output (MIMO) relay-assisted K-user single-input multiple-output (SIMO) interference channels (ICs). Firstly, we propose an iterative optimized reference vector for IA (IORV-IA) algorithm in the perfect channel state information (CSI) scenario. The proposed IORV-IA algorithm not only achieves the alignment of interference signals at each receiver, but also iteratively optimizes the IA reference vector by orthogonalizing the directions of the interference signals and the desired signal. With the optimized IA reference vector, the relay processing matrix and the receiving filter vectors are designed to further improve the system performance. Considering that the relay cannot obtain perfect CSIs in practice due to many factors, and the performance of the IA scheme is very sensitive to this error. Furthermore, we propose a robust transceiver design scheme based on mean square error (MSE) in the imperfect CSI scenario, which minimizes the sum of MSEs in the worst case through iteration. The proposed algorithms are evaluated in terms of the average sum rate and bit error rate (BER) performance and the simulation Article Title results show the advantages of the proposed algorithms over existing centralized IA (CIA) and centralized zero-forcing (CZF) algorithms.