Psoriasis is a chronic immune-mediated skin condition with multiple remissions and relapses. It is characterized mainly by dry itchy skin with scaling, burning sensation and bleeding spots. Conventional treatments include topical steroids, light therapy and oral medications. This paper aims to report a case of palmoplantar psoriasis in a 75-year-old female, presented with symptoms of cracks and excoriation of soles, heel, itching of palms, treated and managed with homoeopathic medicines.