Pss1 Risk of Psychiatric Disorders and Health Care Expenditures Among Patients With Moderate to Severe Psoriasis

Han, Chenglong; Zhao, Ning; Waters, Heidi C.

doi:10.1016/s1098-3015(10)66993-8

Cited by 36 publications

(62 citation statements)

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“…Psoriasis has multiple possible causes, and medical professionals should pay additional attention to recognize all contributing factors of this disease (2,3). It is shown that the prevalence of psychiatric disorders is higher in patients with moderate-to-severe psoriasis (4). Suicide and its related death is higher among these patients (5).…”

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confidence: 99%

Evaluation of Some Psychological Factors in Psoriatic Patients

Fakour

Nourmohammadpour

Gholamali

et al. 2015

European Psychiatry

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BackgroundPsoriasis is a disease which may have direct impact on the psychological and social aspects, particularly due to its visibility. To date, we are unaware of any study showing relationship between psoriasis and psychological parameters such as psychological vulnerability and coping strategies.Objectiveto evaluate the effects of psoriasis on some psychological parameters in an Iranian population.MethodsPatients having histopathologically confirmed psoriasis for at least 6 months attending the Clinic of Razi Hospital and evaluated by PASI,CISS,IPQ-RResultsThere were 101 females and 99 males with the mean age of 43.2 (±16.32). The mean PASI Score was 6.58 ± 6.04. Diffuse skin involvement was the commonest form of disease (133 patients, 66.5%). the highest score for Illness perception belongs to those with genitalia involvement (185.2, worst illness perception) and the lowest score for Illness perception belong to those with nail involvement (168.2). Consistently, the lowest score of facing with the problems (CISS: approach strategy to disease) belongs to those with hand involvement (50.5) whereas the highest score belongs to those with genitalia involvement (60.4). There was significant correlation between psychological vulnerability vs. Illness perception score as well as psychological vulnerability vs. coping strategies score. Surprisingly, PASI score had insignificant relationship with illness perception, coping strategies or psychological vulnerability score.ConclusionPASI score as a representing factor of skin involvement has limited role in predicting effect of psoriasis on mental status and illness perception of psoriatic patients. Psychological vulnerability of patients is the main predicting factor of illness perception and coping strategiesThere were 101 females and 99 males with the mean age of 43.2 (±16.32). The mean PASI Score was 6.58 ± 6.04. Diffuse skin involvement was the commonest form of disease (133 patients, 66.5%). the highest score for Illness perception belongs to those with genitalia involvement (185.2, worst illness perception) and the lowest score for Illness perception belong to those with nail involvement (168.2). Consistently, the lowest score of facing with the problems (CISS: approach strategy to disease) belongs to those with hand involvement (50.5) whereas the highest score belongs to those with genitalia involvement (60.4). There was significant correlation between psychological vulnerability vs. Illness perception score as well as psychological vulnerability vs. coping strategies score. Surprisingly, PASI score had insignificant relationship with illness perception, coping strategies or psychological vulnerability score.There were 101 females and 99 males with the mean age of 43.2 (±16.32). The mean PASI Score was 6.58 ± 6.04. Diffuse skin involvement was the commonest form of disease (133 patients, 66.5%). the highest score for Illness perception belongs to those with genitalia involvement (185.2, worst illness perception) and the lowest score for Illness perception belong...

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confidence: 99%

Evaluation of Some Psychological Factors in Psoriatic Patients

Fakour

Nourmohammadpour

Gholamali

et al. 2015

European Psychiatry

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“…Eczema and psoriasis are seen each in 0.5 % of BD patients which is roughly double of what expected in the general population (Weber et al 2011 ). From a reverse angle, patients with psoriasis have double rates of BD (1.1 % vs. 0.5 %), in comparison to controls (Han et al 2011 ).…”

Section: Dermatological Disordersmentioning

confidence: 75%

Comorbidity

Fountoulakis¹

2014

Bipolar Disorder

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“…It has been observed that the prevalence of anxiety, depression, bipolar disorder or delirium is higher in psoriatic patients than controls. The proportion of patients receiving antidepressants, anxiolytics or antipsychotics was higher in psoriatic patients than controls [26]. In fact, the average total yearly health care cost for psoriasis patients (US $11,369) was significantly higher than for controls ($3,427), placing a large economic burden on patients and the healthcare system.…”

Section: Psoriasis and Co-morbiditiesmentioning

confidence: 99%

Genetic Epidemiology of Psoriasis

2014

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Psoriasis is a chronic, inflammatory, immune-mediated skin condition with a prevalence of 0-11.8% across the world. It is associated with a number of cardiovascular, metabolic, and autoimmune disease co-morbidities. Psoriasis is a multifactorial disorder, influenced by both genetic and environmental factors. Its genetic basis has long been established through twin studies and familial clustering. The association of psoriasis with the HLA-Cw6 allele has been shown in many studies. Recent genome-wide association studies have identified a large number of other genes associated with psoriasis. Many of these genes regulate the innate and adaptive immune system. These findings indicate that a dysregulated immune system may play a major role in the pathogenesis of psoriasis. In this article, we review the clinical and genetic epidemiology of psoriasis with a brief description of the pathogenesis of disease.

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Pss1 Risk of Psychiatric Disorders and Health Care Expenditures Among Patients With Moderate to Severe Psoriasis

Cited by 36 publications

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Evaluation of Some Psychological Factors in Psoriatic Patients

Evaluation of Some Psychological Factors in Psoriatic Patients

Comorbidity

Genetic Epidemiology of Psoriasis

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