2009
DOI: 10.1159/000210547
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Psychiatric Comorbidity in Patients Evaluated for Chronic Epilepsy: A Differential Role of the Right Hemisphere?

Abstract: Introduction: Psychiatric disorders are known to occur frequently in chronic epilepsy. The aim of this study is to investigate the prevalence of psychiatric comorbidity and its relationship to regional cerebral dysfunction in patients admitted to a tertiary epilepsy center for epilepsy surgery. Methods: 217 patients were investigated. A presurgical workup was performed and allowed precise localization of the epileptogenic focus in 156 patients. Sixty-one patients had multifocal or generalized discharges. After… Show more

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Cited by 34 publications
(21 citation statements)
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“…This might be due to the small sample size in the current study. Similar to the study by Sperli et al 26 we did not detect any relation between clinical and demographic factors and comorbid psychiatric disorders.…”
Section: Discussionsupporting
confidence: 91%
“…This might be due to the small sample size in the current study. Similar to the study by Sperli et al 26 we did not detect any relation between clinical and demographic factors and comorbid psychiatric disorders.…”
Section: Discussionsupporting
confidence: 91%
“…In addition, the DSM-IV diagnoses for specific anxiety disorders were not assessed by a standardized clinical interview; however, the scales used to measure anxiety are validated and commonly employed in epileptology. 39 Finally, due to its cross-sectional design, the study could not establish any causal relationship between psychopathology and FLE and GE.…”
Section: Discussionmentioning
confidence: 93%
“…A clear lateralization could not be demonstrated for psychopathology (including anxiety) in epilepsy patients by several studies (Altshuler et al, 1990, Sperli et al, 2009) nor could a clear localization (temporal lobe versus extract temporal lobe epilepsy) be shown (Swinkels et al, 2006).…”
Section: Localization/ Lateralizationmentioning
confidence: 94%