Psychiatric Disorders Before and After Living-Related Transplantation

Fukunishi, Isao; Sugawara, Yuka; Takayama, Tadatoshi; Makuuchi, Masatoshi; Kawarasaki, Hideo; Surman, Owen S.

doi:10.1176/appi.psy.42.4.337

Cited by 112 publications

(85 citation statements)

References 9 publications

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“…Donors displayed a decrease in anxious depression and increase in elevated mood scales compared to the preoperative period. However, negative psychosocial outcomes such as clinical depression and somatization have been reported after LRLT in a number of studies (13,14). In the study by Erim et al (15), 6 (14%) living donors -all female -had transient, but severe psychiatric disturbance as depressive disorders in 5 and posttraumatic stress disorder in 1.…”

Section: Discussionmentioning

confidence: 99%

Assessment of living donors with respect to pre- and posttransplant psychosocial properties and posttransplant family functioning in pediatric liver transplantation

Gökçe

Durmaz²,

Gürsu³

et al. 2011

Turk J Gastroenterol

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Section: Discussionmentioning

confidence: 99%

Assessment of living donors with respect to pre- and posttransplant psychosocial properties and posttransplant family functioning in pediatric liver transplantation

Gökçe

Durmaz²,

Gürsu³

et al. 2011

Turk J Gastroenterol

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“…17,18 However, their data could not be extrapolated to ALDLT because of the lower morbidity (Ͻ2%) and mortality (0.02%) in live donor kidney transplantation. 19 In ALDLT, with few exceptions, 20,21 published donor HRQL studies are retrospective and not longitudinal. [22][23][24][25][26] The aim of this study was to prospectively and longitudinally quantify HRQL issues of live liver donors in ALDLT.…”

mentioning

confidence: 99%

Donor quality of life before and after adult-to-adult right liver live donor liver transplantation

Chan

Liu

et al. 2006

Liver Transpl

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Donor right hepatectomy for adult-to-adult live donor liver transplantation (ALDLT) is a major surgical operation for the benefit of the recipient. Justification of procedure mandates knowledge of the possible physical and psychological negative effects on the donor. We prospectively and longitudinally quantified donor quality of life using generic and condition-specific questionnaires up to 1 year. The generic questionnaires were the Karnofsky Performance Status scale and the Chinese (Hong Kong) version of the Medical Outcomes Study 36-Item Short-Form Survey, which measures 8 health concepts: 4 physical components and 4 mental components. Within 1 year, 30 consecutive donors were included. These 11 male and 19 female donors (36.7% and 63.3%, respectively) had a median age of 35 years (range, 21-56 years). There was no donor mortality or major complications. Donor quality-of-life worsening was most significant in the first 3 postoperative months, particularly among the physical components. The physical and mental components returned to the previous levels in 6 to 12 months' time, though the Karnofsky performance scores were slightly lower at 1 year (P ϭ 0.011). Twenty-six (86.7%) donors declared that they would donate again if there were such a need and it were technically possible. It was noticed that older donors were more likely to express unwillingness to donate again. In conclusion, the temporary worsening of donor quality of life substantiates ALDLT as an acceptable treatment modality. Liver Transpl 12: 1529-1536, 2006.

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“…There is heterogeneity in the results of these studies, and the findings need to be interpreted with caution because psychiatric diagnoses were determined by means of psychometric scales and only in few cases by a comprehensive clinical interview. 7,[8][9][10][11][12] Reported prevalence rates of psychiatric disorders among OLT candidates vary from 15% to 50%. [8][9][10][11][12] Another recent study describing psychological characteristics of a large sample of OLT candidates reports that more than half the patients presented at least mild levels of depression, and more than one third were affected by clinically elevated levels of anxiety, suggesting a greater incidence of depression and anxiety than previously reported.…”

mentioning

confidence: 99%

Predictors of psychiatric disorders in liver transplantation candidates: Logistic regression models

Rocca

2003

Liver Transplantation

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This study has two goals. The first goal is to assess the prevalence of psychiatric disorders in orthotopic liver transplantation (OLT) candidates by means of standardized procedures because there has been little research concerning psychiatric problems of potential OLT candidates using standardized instruments. The second goal focuses on identifying predictors of these psychiatric disorders. One hundred sixty-five elective OLT candidates were assessed by our unit. O rthotopic liver transplantation (OLT) is an accepted standard of care for end-stage liver disease. The pre-OLT period is marked by declining physical function, adjustment-related anxiety and depression, and development of organic brain deficits. [1][2][3][4] Although several psychiatric follow-up studies are available for recipients and donors after OLT, [5][6][7] there are few studies concerning the psychiatric status of potential OLT candidates before OLT. There is heterogeneity in the results of these studies, and the findings need to be interpreted with caution because psychiatric diagnoses were determined by means of psychometric scales and only in few cases by a comprehensive clinical interview. 7,[8][9][10][11][12] Reported prevalence rates of psychiatric disorders among OLT candidates vary from 15% to 50%. [8][9][10][11][12] Another recent study describing psychological characteristics of a large sample of OLT candidates reports that more than half the patients presented at least mild levels of depression, and more than one third were affected by clinically elevated levels of anxiety, suggesting a greater incidence of depression and anxiety than previously reported. 13

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Psychiatric Disorders Before and After Living-Related Transplantation

Cited by 112 publications

References 9 publications

Assessment of living donors with respect to pre- and posttransplant psychosocial properties and posttransplant family functioning in pediatric liver transplantation

Assessment of living donors with respect to pre- and posttransplant psychosocial properties and posttransplant family functioning in pediatric liver transplantation

Donor quality of life before and after adult-to-adult right liver live donor liver transplantation

Predictors of psychiatric disorders in liver transplantation candidates: Logistic regression models

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