Psychiatric manifestations of neurocysticercosis: a study of 38 patients from a neurology clinic in Brazil.

Forlenza, Orestes Vicente; Filho, A. H. G. Vieira; Nobrega, J. P. S.; Machado, Luı́s dos Ramos; Barros, Nélio Garcia de; Camargo, C H de; Silva, M F da

doi:10.1136/jnnp.62.6.612

Cited by 141 publications

(109 citation statements)

References 34 publications

Supporting

Mentioning

101

Contrasting

Unclassified

Order By: Relevance

“…Our patient showed no evidence of obstructive hydrocephalus with cerebral edema as the most likely cause of her papilledema, unlike a recently reported case of neurocysticercosis in which diplopia and headache were described [11]. Small case series have suggested that mania is the most common mood disorder in neurocysticercosis; however, a larger prospective study of psychiatric disorders in 38 patients with neurocysticercosis showed that depression was most prevalent (12/23 patients with psychiatric disease, or 52%) [12].…”

Section: Discussioncontrasting

confidence: 46%

Neurocysticercosis Presenting as Bipolar Disorder and Chronic Papilledema: A Rare Case Report and Review

Sune¹

2014

J Clin Exp Ophthalmol

View full text Add to dashboard Cite

A 40 year old female presented with mania, abnormal behaviour, headache & gradual progressive diminution of vision & history of pork consumption. Anterior segment examination OU was normal. Fundus of both eyes showed B/L established papilledema. Visual Acuity was 20/125 both eyes. CT & MRI with contrast revealed multiple well defined rounded CSF density cysts with a central mural nodule representing a scolex showing ring enhancement and perilesional edema. The largest lesion was 7.7×9 mm and multiple lesions were noted in both cerebral hemisphere and internal capsular regions, right cerebellar hemisphere and pons suggestive of disseminated neurocysticercosis. B-scan revealed disc edema and increased optic nerve diameter by more than 5 mm in both eyes confirming papilledema. She was prescribed albendazole, praziquantel, steroids, mannitol, acetazolamide and lithium. With this treatment her mania and headache resolved and her vision in both eyes improved to 20/40. Fundus examination after 3 months showed resolving papilledema. CT & MRI now showed marked decrease in number and regression in size of cyst and lesions. Bipolar disorder (mania & abnormal behavior) can be the first presenting sign of neurocysticercosis and papilledema. The probable explanation for maniac presentation in neurocystecercosis is due to some changes in neurotransmitter level. Papilledema was due to raised ICP suggested by perilesional edema in CT scan & MRI, and disc edema with increased optic nerve diameter in both eyes by more than 5 mm in B-scan.

show abstract

Section: Discussioncontrasting

confidence: 46%

Neurocysticercosis Presenting as Bipolar Disorder and Chronic Papilledema: A Rare Case Report and Review

Sune¹

2014

J Clin Exp Ophthalmol

View full text Add to dashboard Cite

show abstract

“…14 Neurocysticercosis may also be associated with inflammatory cerebral aneurysm and subarachnoid hemorrhage, 27 temporal lobe epilepsy, 31 psychiatric manifestations, 24 and stroke. Recently, a link between NCC and oncogenesis has been postulated.…”

Section: Resultsmentioning

confidence: 99%

Spinal cord cysticercosis: neurosurgical aspects

Colli¹,

Valênça²,

Carlotti³

et al. 2002

FOC

View full text Add to dashboard Cite

Object The authors report their experience in the treatment of 12 symptomatic patients with intradural spinal neurocysticercosis. Methods The mean age of the 12 patients was 33 years. There were eight female and four male patients. Cysticercosis was present in association with hydrocephalus in nine cases. In nine of 12 patients the spinal lesion was confined to the thoracic or lumbar spinal cord, and in three the cysticerci occupied the cervical region. In all patients with hydrocephalus nerve root symptoms developed seven to 48 months later (mean 27.6 ± 15.5 months). In one patient hydrocephalus was absent, but he presented with cysticercal meningitis 24 months before spinal cord compression developed. Presenting symptoms suggesting spinal cysticercosis included muscular weakness (67%), pain (67%), and sphincter disturbance (25%). Neurological examination demonstrated a motor deficit in nine patients, sensory deficit in four, and radicular pain in three. The prognosis was worse in patients with moderate-to-severe arachnoiditis and spinal cord compression compared with those with isolated nerve roots involvement in whom outcome was favorable. Ten patients underwent laminectomy, after which neurological status improved in 44%, remained unchanged in 33%, or worsened in 22.2%. Conclusions The authors discuss their findings in these cases. Additionally they briefly review the literature, patho-physiology, and therapeutic and/or surgical strategies involved in this disease.

show abstract

“…A number of patients with NCC present with psychiatric and intellectual impairment symptoms [15,16].…”

Section: Clinical Featuresmentioning

confidence: 99%

Therapy for neurocysticercosis

Takayanagui

2004

Expert Review of Neurotherapeutics

View full text Add to dashboard Cite

Psychiatric manifestations of neurocysticercosis: a study of 38 patients from a neurology clinic in Brazil.

Cited by 141 publications

References 34 publications

Neurocysticercosis Presenting as Bipolar Disorder and Chronic Papilledema: A Rare Case Report and Review

Neurocysticercosis Presenting as Bipolar Disorder and Chronic Papilledema: A Rare Case Report and Review

Spinal cord cysticercosis: neurosurgical aspects

Therapy for neurocysticercosis

Contact Info

Product

Resources

About