Psychiatric profile and quality of life of subjects with excess weight treated with transcranial direct current stimulation combined with a hypocaloric diet

Natividade, Gabriella Richter da; Araújo, Carina de; Fitz, Raquel Crespo; Brietzke, Elisa; Schestatsky, Pedro; Gerchman, Fernando

doi:10.1080/1028415x.2019.1693319

Cited by 4 publications

(9 citation statements)

References 40 publications

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“…Even without finding results that support the adoption of the interventions under investigation, this approach has become progressively more accepted [ 77 ]. On the other hand, traditional psychiatric treatments, such as neuromodulatory approaches, have been investigated to target both psychopathology and metabolic variables with some promising results [ 78 ].…”

Section: Discussionmentioning

confidence: 99%

A Possible Antidepressive Effect of Dietary Interventions: Emergent Findings and Research Challenges

Ceolin

Breda

Koning

et al. 2022

Curr Treat Options Psych

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Section: Discussionmentioning

confidence: 99%

A Possible Antidepressive Effect of Dietary Interventions: Emergent Findings and Research Challenges

Ceolin

Breda

Koning

et al. 2022

Curr Treat Options Psych

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“…Risk of selection bias due to inadequate random sequence generation was rated as high for two studies [34,51] and high due to inadequate allocation concealment for one study [51]. Risk of performance bias was judged to be high due to inadequate blinding of participants and personnel in four studies [36,54,55,59]. Risk of detection bias was held to be high due to inadequate blinding of outcome assessments in one study [55].…”

Section: Risk Of Biasmentioning

confidence: 99%

“…Risk of performance bias was judged to be high due to inadequate blinding of participants and personnel in four studies [36,54,55,59]. Risk of detection bias was held to be high due to inadequate blinding of outcome assessments in one study [55]. Risk of attrition bias due to incomplete outcome data was found to be high in three studies [24,57,65].…”

Section: Risk Of Biasmentioning

confidence: 99%

“…Risk of attrition bias due to incomplete outcome data was found to be high in three studies [24,57,65]. High risk of reporting bias due to selective reporting was found in four studies [53,55,60,62]. Risk of bias from other sources was found in three studies [40,55,62].…”

Section: Risk Of Biasmentioning

confidence: 99%

“…High risk of reporting bias due to selective reporting was found in four studies [53,55,60,62]. Risk of bias from other sources was found in three studies [40,55,62]. Meta-analyses were conducted for each of the primary outcomes-tinnitus, depression, and anxiety.…”

Section: Risk Of Biasmentioning

confidence: 99%

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Determining the Effects of Transcranial Direct Current Stimulation on Tinnitus, Depression, and Anxiety: A Systematic Review

et al. 2022

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(1) Background: Tinnitus is the awareness of a sound in the absence of an external source. It affects around 10–15% of people, a significant proportion of whom also experience symptoms such as depression or anxiety that negatively affect their quality of life. Transcranial direct current stimulation (tDCS) is a technique involving constant low-intensity direct current delivered via scalp electrodes. It is a potential treatment option for tinnitus, as well as tinnitus-related conditions such as depression and anxiety. This systematic review estimates the effects of tDCS on outcomes relevant to tinnitus. In addition, it sheds light on the relationship between stimulation parameters and the effect of tDCS on these outcomes; (2) Methods: Exhaustive searches of electronic databases were conducted. Randomised controlled trials were included if they reported at least one of the following outcomes: tinnitus symptom severity, anxiety, or depression. Where available, data on quality of life, adverse effects, and neurophysiological changes were also reviewed. GRADE was used to assess the certainty in the estimate; (3) Results: Meta-analyses revealed a statistically significant reduction in tinnitus (moderate certainty) and depression (low certainty)-but not anxiety-following active tDCS compared to sham control. Network meta-analyses revealed potential optimal stimulation parameters; (4) Conclusions: The evidence synthesised in this review suggests tDCS has the potential to reduce symptom severity in tinnitus and depression. It further narrows down the number of potentially optimal stimulation parameters.

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Effects of transcranial direct current stimulation associated with hypocaloric diet on glucose homeostasis in obesity

Araújo

Fitz

Natividade

et al. 2022

Obesity

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ObjectiveThe aim of this study was to test the effects of repetitive active transcranial direct current stimulation (tDCS) over the right dorsolateral prefrontal cortex (rDLPFC) associated with a hypocaloric diet on glucose homeostasis in people with excessive weight.MethodsAdults with overweight or obesity were selected in a randomized, double‐blind pilot study to complete 4 weeks (20 sessions) of fixed‐dose tDCS (2 mA, 20 minutes) delivered over the rDLPFC and associated with a standard hypocaloric diet. Participants were randomly assigned (1:1) and stratified by sex to the active tDCS group (active) or the sham tDCS group (sham). Changes in glucose homeostasis were assessed in a 4‐hour liquid meal tolerance test, performed before and after the intervention.ResultsTwenty‐eight participants were randomized (79% with obesity; mean [SD] age 37.6 [5.8] years). After the intervention, fasting plasma glucose (mean [95% CI], −7.8 mg/dL [−14.0 to −1.6]) and insulin levels (−7.7 μIU/mL [−13.9 to −1.6]) decreased in the active compared with the sham. Similarly, the Matsuda insulin sensitivity index increase in the active (4.7 pmol−1 × mmol−1 [1.6 to 7.8]) compared with the sham (0.6 pmol−1 × mmol−1 [−1.4 to 3.2]).ConclusionsRepetitive, active tDCS over the rDLPFC could be a promising noninvasive technique to improve glucose homeostasis in individuals with overweight or obesity on a low‐calorie diet, highlighting the importance of investigating this intervention modality in individuals with type 2 diabetes mellitus.

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Psychiatric profile and quality of life of subjects with excess weight treated with transcranial direct current stimulation combined with a hypocaloric diet

Cited by 4 publications

References 40 publications

A Possible Antidepressive Effect of Dietary Interventions: Emergent Findings and Research Challenges

A Possible Antidepressive Effect of Dietary Interventions: Emergent Findings and Research Challenges

Determining the Effects of Transcranial Direct Current Stimulation on Tinnitus, Depression, and Anxiety: A Systematic Review

Effects of transcranial direct current stimulation associated with hypocaloric diet on glucose homeostasis in obesity

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