Psychiatric Symptoms, Risky Behavior, and HIV Infection

Ge, Woody; Metzger, David S.; Navaline, Helen; McLellan, Thomas; Cp, O'Brien

doi:10.1037/e495582006-010

Cited by 18 publications

(20 citation statements)

References 16 publications

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“…ASI drug and alcohol scores were higher for HIV? participants relative to the HIV-group, which agrees with the literature (Kalichman et al 1994;Woody et al 1997).…”

Section: Discussionsupporting

confidence: 91%

“…Metzger et al (1993) found that the intensity and frequency of psychiatric symptoms is highly associated with intravenous drug use and continual or continuous needle sharing among opioid-dependent patients (Metzger et al 1993). In a longitudinal study of heroin addicts, Woody et al (1997) confirmed the previous finding by reporting higher psychiatric symptom levels among drug-injectors versus noninjectors (Woody et al 1997). This positive relationship between psychiatric symptomatology and drug use is particularly concerning because they may interact synergistically to magnify an individual's risk for HIV beyond the separate risks of SMI and drug use .…”

Section: Introductionsupporting

confidence: 73%

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Using Psychiatric Symptomatology to Assess Risk for HIV Infection in Individuals with Severe Mental Illness

Rothbard

Blank

2011

Community Ment Health J

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In this study, we use the Colorado Symptom Index, a measure of psychiatric symptomatology, to identify vulnerable subgroups within the severely mentally ill population at elevated risk for HIV infection. Baseline data on 228 HIV positive and 281 HIV negative participants from two clinical trials were used. With years to HIV diagnosis as our primary endpoint, Kaplan-Meier estimates were calculated to find a CSI cut-off score, and a Cox proportional hazards model was used to obtain relative risks of infection for the two CSI categories created by the cut point. We found that a CSI score ≥ 30 was associated with a 47% increased risk for HIV infection (P < 0.01). While this study establishes the foundation for using CSI scores to identify a vulnerable subgroup within the SMI community, further studies should develop effective approaches to mitigate psychiatric symptomatology in order to examine the impact on HIV transmission risky behaviors.

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“…ASI drug and alcohol scores were higher for HIV? participants relative to the HIV-group, which agrees with the literature (Kalichman et al 1994;Woody et al 1997).…”

Section: Discussionsupporting

confidence: 91%

Section: Introductionsupporting

confidence: 73%

Using Psychiatric Symptomatology to Assess Risk for HIV Infection in Individuals with Severe Mental Illness

Rothbard

Blank

2011

Community Ment Health J

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“…ASPD has been associated with poorer treatment outcomes, including worse psychosocial functioning, more legal problems, and more problematic substance use in many (Basu et al, 2004;Cacciola et al, 1996;Compton et al, 2003;Fridell et al, 2006;Grella et al, 2003;King et al, 2001;Leal et al, 1994) but not all (Brooner et al, 1998;Crits-Cristoph et al, 1999;McKay et al, 2000;Messina et al, 2002Messina et al, , 2003 studies. Among patients with DUDs, comorbid ASPD is associated with higher levels of drug and sexual HIV risk behaviors Disney et al, 2006;Fals-Stewart et al, 2003;Kelley and Petry, 2000;Ladd and Petry, 2003;Woody et al, 1997). However, ASPD has been an inconsistent predictor of response to HIV risk reduction interventions (Compton et al, , 2000bMcCusker et al, 1995;Woody et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

Antisocial behavioral syndromes and DSM-IV drug use disorders in the United States: Results from the National Epidemiologic Survey on Alcohol and Related Conditions

Goldstein

Compton

Pulay

et al. 2007

Drug and Alcohol Dependence

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Background-Antisocial behavioral syndromes, including antisocial personality disorder (ASPD), syndromal adult antisocial behavior (AABS) without conduct disorder (CD) before age 15, and CD without progression to ASPD ("CD only") are highly comorbid with drug use disorders (DUDs). Among patients in DUD treatment, antisocial syndromes are associated with greater severity and poorer outcomes. Comparative data concerning associations of antisocial syndromes with clinical characteristics of DUDs among general population adults have not previously been available. This study describes associations of antisocial syndromes with clinical characteristics of lifetime Diagnostic and Statistical Manual -Version IV DUDs in the general U.S. adult population. Methods-This report is based on the 2001-2002 National Epidemiologic Survey on Alcohol andRelated Conditions (n=43,093, response rate=81%). Respondents (n=4,068) with lifetime DUDs were classified according to whether they met criteria for ASPD, AABS, "CD only," or no antisocial syndrome. Associations of antisocial syndromes with clinical characteristics of DUDs were examined using logistic regression.Results-Antisocial syndromes were significantly associated with the phenomenology of DUDs, particularly ASPD with the most severe clinical presentations. Associations with AABS were similar to those with ASPD; those with "CD only" were weak, inconsistent, and not statistically significant. Patterns of associations differed little between men and women.

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“…5 On the other hand, several psychiatric conditions including depression may predispose individuals to acquiring HIV infection as a consequence of their influence on behavior. 6,7 There is good evidence from the international researchparticularly from developed countries, that the prevalence of depression in PLHAs is higher than those with HIVnegative controls. 8,9 However, very little is known about their mental problems and subsequent needs in developing countries like India, which are most affected by the HIV-epidemic.…”

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confidence: 99%

A study on depression in people living with HIV/AIDS in South-West part of Uttar Pradesh, India

Rai

Verma

2015

SE Asia J. Pub. Health

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HIV/AIDS and depression are often thought to be interlinked. HIV positive cases may trigger symptoms of depression which, in turn, may result in risky sexual behavior and spread of HIV. Interviews were conducted in 104 patients of HIV/AIDS at the Anti-Retroviral Therapy (ART) Clinic of a teaching hospital in Uttar Pradesh (India) to study depression and examine its prevalence and association, if any, with some socio-demographic and clinical variables. The tools used to assess anxiety and depression and their severities were General Health Questionnaire (GHQ) 28 and Montgomery-Asberg Depression Rating Scale (MADRS) . The majority of patients were of age 35 years & above (62%), males (67%), married (85%), Hindus (88%), literate (73.1%), unemployed (35%) and of upper-lower socio-economic status (52%). Significant association of depression was found with religion, occupation and socio-economic status. Depression and anxiety were also found to be significantly associated with each other. There was, however, no association of depression with respondents' age, gender, marital status, education, habitat, income, duration of illness from HIV/AIDS and the CD4 count. The high prevalence rate (67.3%) of depression amongst HIV patients in our study may be taken as marker to alert Counsellors of country's ART Clinics for possible risk of depression in HIV patients. The above findings however, should be interpreted in the light of the fact that a parallel control group in the study was not included, studied sample was not large enough and the tools used to study the subjects for depression and anxiety were not adequately standardized.

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Psychiatric Symptoms, Risky Behavior, and HIV Infection

Cited by 18 publications

References 16 publications

Using Psychiatric Symptomatology to Assess Risk for HIV Infection in Individuals with Severe Mental Illness

Using Psychiatric Symptomatology to Assess Risk for HIV Infection in Individuals with Severe Mental Illness

Antisocial behavioral syndromes and DSM-IV drug use disorders in the United States: Results from the National Epidemiologic Survey on Alcohol and Related Conditions

A study on depression in people living with HIV/AIDS in South-West part of Uttar Pradesh, India

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