The primary purpose of this study is to reveal the studies on Cognitive Ergonomics (CE), determine general trends, show the gaps and extract new knowledge from the body of the literature. Ergonomics evolved from classical to physical and CE. The literature review on CE is quite limited. Thus, we conducted the most comprehensive review of the CE literature between 1974-2021 to provide an original perspective and extend what is known through analysis, modeling and introduction of new theories. 1958 papers identified from Electronic Databases, 254 of them were selected and included in the analysis. The PRISMA technique was used for the systematic reviews of CE literature with the statistical evidences and detailed discussions. As a result, CE studies were classified into 4 main groups with 13 subgroups. This study offers, constructive analyses of scientific publications on CE, by combing the literature and summarizing the current knowledge in a cogent way.Thus, a basis to enhance future applications in CE was provided. It is predicted that CE activities will be used to solve cognitive problems in more and more areas in the rapidly digitalizing world and will take their place soon especially in Metaverse application and softwares.