2010
DOI: 10.1155/2010/302693
|View full text |Cite
|
Sign up to set email alerts
|

Psychological Stress Alters Ultrastructure and Energy Metabolism of Masticatory Muscle in Rats

Abstract: To investigate the effects of psychological stress on the masticatory muscles of rats, a communication box was applied to induce the psychological stress (PS) in rats. The successful establishment of psychological stimulation was confirmed by elevated serum levels of adrenocorticotropic hormone (ACTH) and changed behaviors in the elevated plusmaze apparatus. The energy metabolism of the bilateral masseter muscles was tested via chemocolorimetric analysis, whereas muscle ultrastructure was assessed by electron … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

2
19
0
8

Year Published

2011
2011
2021
2021

Publication Types

Select...
8
1

Relationship

0
9

Authors

Journals

citations
Cited by 30 publications
(29 citation statements)
references
References 35 publications
2
19
0
8
Order By: Relevance
“…Behavioral stress increased mechanical-evoked excitability of hindlimb muscle afferents in male rats; however, no preferential effect on unmyelinated and myelinated fibers was noted [15]. Also, peripheral effects of stress on non-neural tissue cannot be excluded [16]. In this study FS increased the spontaneous activity and reduced the threshold dose of ATP required to activate TMJ units in deep, but not superficial laminae, consistent with a peripheral effect; however, the responses to mechanical stimulation of facial skin were not altered.…”
Section: Discussionmentioning
confidence: 99%
“…Behavioral stress increased mechanical-evoked excitability of hindlimb muscle afferents in male rats; however, no preferential effect on unmyelinated and myelinated fibers was noted [15]. Also, peripheral effects of stress on non-neural tissue cannot be excluded [16]. In this study FS increased the spontaneous activity and reduced the threshold dose of ATP required to activate TMJ units in deep, but not superficial laminae, consistent with a peripheral effect; however, the responses to mechanical stimulation of facial skin were not altered.…”
Section: Discussionmentioning
confidence: 99%
“…Indeed, response latencies of TMJ neurons in superficial and deep laminae to ATP were reduced after FS and a greater percentage of neurons in both laminae were activated by the lowest dose of ATP. We also cannot exclude that effects on non‐neural peripheral tissues could have contributed to these results as repeated psychological stress caused structural and metabolic changes in masseter muscle of rats (Chen et al. , 2011), whereas in humans, acute mental stress significantly affected hemodynamic variables and EMG activity in jaw muscles (Hidaka et al.…”
Section: Discussionmentioning
confidence: 99%
“…Social isolation can induce chronic psychological stress, hypoactivity, reduced antioxidant activity and increased anaerobic metabolism of glucose in 21 days (Zhuravliova et al 2009; Djordjevic et al 2010). In experimental studies, both physical and psychological stress can lead to dysfunction of mitochondrial activity, increased lactate accumulation in the masticatory skeletal muscles and disruption of muscle fibres, presenting loss of striations and nucleus with intercellular oedema (Antonova, 2008; Chen et al 2010 b ). Cell damage was attributed to impaired oxidative metabolism due to oxidative damage of the mitochondrial electron transport chain and increased activity of glycolytic enzymes, such as lactate dehydrogenase and hexokinase, in chronically stressed animals (Antonova, 2008; Zhuravliova et al 2009; Djordjevic et al 2010; Chen et al 2010 a ).…”
Section: Discussionmentioning
confidence: 99%