Psychomimetic effects of pentazocine and dihydrocodeine tartrate.

Abstract

a diet sheet in English had had the diet satisfactorily explained compared with three out of four who received a sheet in the native language and seven out of the I 1 who received a sheet in both languages.

Mania associated with codeine and paracetamol

“…Agitation and hypomania have been described with the use of meberidine [20]. Taylor et al [21] reported hallucinations and marked euphoria, occurring in 10% and 4% of general hospital patients taking pentazocine and dihydrocodeine, respectively. Both reports noted that these symptoms are often underreported or misattributed, often to functional psychiatric illness.…”

Oral narcotic analgesics

“…Psychomimetic reactions in the form of vivid dreams, disorientation, hallucinations, and panic occur in up to 10% of patients taking pentawcine; this appears to be related to pentawcine's affinity for the sigma opioid receptor. 13 Occasionally, pentawcine is abused in combination with the antihistamine tripelennamine hydrochloride (known as ''T's and blues"). Consequently, penrawcine is now available in combination with low-dose naloxone hydrochloride (Talwin Nx); this formulation allows retention of its analgesic effect but offiets its illicit use.…”

The use of analgesics

“…11,16,65,66 All drugs in this class precipitate withdrawal and return of pain in patients stabilized on the pure narcotic agonists. For this reason, patients should not receive an agonist with partial antagonist activity concomitantly with a pure agonist.…”