The relation between the presence or absence of early immobilization and sensory restriction and current intellectual functioning, language comprehension, and emotional and behavioral patterns was investigated in 30 children with phenylketonuria. The 16 children who had experienced immobilization and sensory restriction, as defined, differed significantly from the other 14 children. In intelligence (WISC) and vocabulary (PPVT) tests, a 20-point difference in Intelligence Quotient was documented between the groups. The incidence of serious behavioral pathology was markedly increased in the children who were subjected to immobilization and sensory restriction during the first three years of life.
SpeculationPractices of medical care commonly employed in pediatric hospitals can substantially affect the future intellectual capacity and behavioral pattern of children with phenylketonuria. Similarly, immobilization and sensory restriction might affect other young pediatric patients unfavorably in the presence of other deleterious influences during hospitalization. One out of four children in pediatric hospitals is subjected to a significant degree of sensory restriction and/or immobilization.