Psychosis associated with bromvalerylurea abuse in a patient with traumatic brain injury

Kuo, Chun-Ya; Liu, Chih-Min; Chang, Li-Ren

doi:10.1016/j.genhosppsych.2011.10.010

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“…This would accord with multi-factorial understandings of the stress-vulnerability hypothesis, postulated by Zubin and Spring [7], where brain injury, genetic susceptibility and other risk factors would cumatively combine to increase risk of psychotic disorder. Case reports, for example, have reported psychosis in persons with brain injury to be potentiated by use of the analgesic sedative bromvaleylurea [8] and even chlorpromazine [9]. This, thus, indicates an underlying susceptibility in patients with brain injury to psychosis, which maybe potentiated pharmacologically.…”

Section: Introductionmentioning

confidence: 99%