Psychotropic Medication Use in Pediatric Patients With Cancer

Pao, Maryland; Ballard, Elizabeth D.; Rosenstein, Donald L.; Wiener, Lori; Wayne, Alan S.

doi:10.1001/archpedi.160.8.818

Cited by 30 publications

(18 citation statements)

References 35 publications

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“…In a 2006 study, the recorded percentage of pediatric oncology patients who were prescribed antidepressants was approximately 10.2% (Portteus et al, 2006). Pao, Ballard, Rosentein, Wiener, and Wayne (2006) reported that the prescription rate for psychotropic drugs in the pediatric population had reached an estimated 6%, with stimulant and antidepressant agents most commonly prescribed. However, no cross-sectional study has ever looked at the use of psychotropic medications in AYAs with cancer.…”

Section: Treatment For Anxiety and Depressionmentioning

confidence: 99%

Treatment of Anxiety and Depression in Adolescents and Young Adults With Cancer

Lauer

2015

J Pediatr Oncol Nurs

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Adolescents and young adults (AYAs) with cancer are a unique population of patients who experience a period of intense and dramatic life changes when they are diagnosed. Overall, AYAs with cancer are resilient; however, their psychosocial needs are often underestimated or unmet. Currently, there are inconsistencies in how AYAs are screened and treated for anxiety and depression. Barriers to treatment include clinicians' lack of confidence in distinguishing between side effects of treatment and depression/anxiety. Additional barriers include the black box warning for prescribing antidepressants and difficulty partnering with mental health professionals. This article seeks to provide recommendations for pediatric oncology clinicians on how to identify and address anxiety and depression in AYAs and how to partner with mental health professionals in their treatment, and it suggests directions for future research.

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Section: Treatment For Anxiety and Depressionmentioning

confidence: 99%

Treatment of Anxiety and Depression in Adolescents and Young Adults With Cancer

Lauer

2015

J Pediatr Oncol Nurs

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“…In the US, only fluoxetine, sertraline and escitalopram have pediatric Food and Drug Administration (FDA) indications (FDA resources page 2013). Investigators have found that antidepressant medications and psychological therapies play an important role in the treatment of anxiety and depression in the childhood cancer population (Pao 2006, Kurtz 2010). Researchers at Children’s Medical Center in Dallas noted that the prevalence of antidepressant use in pediatric oncology patients was 10.2% at their institution which was higher than reported rates of depression (4–8%) and antidepressant treatment (1%) in the general population (Portteus 2006).…”

Section: Assessment/treatmentmentioning

confidence: 99%

“…Researchers at Children’s Medical Center in Dallas noted that the prevalence of antidepressant use in pediatric oncology patients was 10.2% at their institution which was higher than reported rates of depression (4–8%) and antidepressant treatment (1%) in the general population (Portteus 2006). In a small retrospective study at the National Institutes of Health, 7% of children involved in cancer research trials were prescribed antidepressant medications (Pao 2006). Kersun et al (2007) reported that 50% of pediatric oncologists at Children’s Hospital of Philadelphia prescribed SSRIs for their patients.…”

Section: Assessment/treatmentmentioning

confidence: 99%

Updates in paediatric psycho-oncology

Mavrides

Pao

2014

International Review of Psychiatry

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Childhood cancer accounts for less than 2% of all cancers diagnosed each year. About 12–14,000 children will be diagnosed in a given year with any type of cancer. Over the past fifty years, treatments and cure rates have improved from 10–20% five year survival rates to between 80–85% five year survival rates. Psychosocial support of children with cancer and their families has grown and has been more fully integrated into pediatric care over the past five decades. Increasing acceptance of the importance of addressing mental health has led to oncologists referring patients to specific resources and services. This paper provides updated information on psychosocial issues for those who treat children and adolescents with cancer and focuses on unique challenges for the pediatric psycho-oncologist.

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“…SSRIs are effective and well‐tolerated first line treatments for depression in the general pediatric population, especially in combination with CBT . Small studies demonstrate tolerability and efficacy in children with cancer . There is widespread prescribing of anti‐depressants by mental health professionals and pediatric oncologists, sometimes without mental health follow‐up, highlighting the need for access to specialized psychiatric consultation.…”

Section: Resultsmentioning

confidence: 99%

Psychosocial Interventions and Therapeutic Support as a Standard of Care in Pediatric Oncology

Steele

Mullins

et al. 2015

Pediatric Blood & Cancer

113

122

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Research indicates that a subset of youths with childhood cancer and their parents will experience significant psychological distress throughout the course of their illness. Importantly, the existing literature indicates that psychosocial support is beneficial in decreasing symptoms of distress in these families. The aim of the current review is to determine the extent of the evidence to support a standard of psychosocial care for children and their families throughout the cancer trajectory; thus, we examined the research related to psychosocial outcomes in youth with cancer and their parents. Pediatr Blood Cancer © 2015 Wiley Periodicals, Inc.

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Psychotropic Medication Use in Pediatric Patients With Cancer

Abstract: This study suggests that psychotropic medications are commonly prescribed to children and adolescents with cancer. Clinical safety and efficacy trials are needed in medically ill children at high risk for mood and anxiety symptoms.

Cited by 30 publications

References 35 publications

Treatment of Anxiety and Depression in Adolescents and Young Adults With Cancer

Treatment of Anxiety and Depression in Adolescents and Young Adults With Cancer

Updates in paediatric psycho-oncology

Psychosocial Interventions and Therapeutic Support as a Standard of Care in Pediatric Oncology

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