PTSD and depression as predictors of physical health-related quality of life in tobacco-dependent veterans

Impact of comorbid depression on quality of life in male combat Veterans with posttraumatic stress disorder

“…The only PTSD cluster that demonstrated significant relationships with these two domains was numbing, with small to medium-sized effects. These findings were consistent with past research suggesting that depression has a stronger influence on decreased quality of life than does PTSD [20,22]. Past studies have also produced similar findings regarding the importance of the PTSD numbing cluster to quality of life in Veterans with PTSD [9,18], and this study supports and extends those findings by suggesting that, of all the PTSD symptom clusters, numbing has the largest negative association with quality of life.…”

“…Likewise, in a sample of Veterans with PTSD, researchers found that depression predicted overall physical-health-related quality of life, while PTSD did not, although analysis of the quality of life subscales provided a more nuanced picture of the findings. While depressive symptoms predicted physical and role functioning scales, both depressive symptoms and PTSD independently predicted general health and bodily pain scales, and depression and PTSD interacted to predict vitality and social functioning scales [22]. Taken together, the existent research suggests that PTSD and depression make unique contributions to decreased quality of life, but that depression exerts a stronger influence.…”

Patterns of DSM-5 posttraumatic stress disorder and depression symptoms in an epidemiological sample of Chinese earthquake survivors: A latent profile analysis

“…These differences in associations between specific symptom presentations of PTSD and depression with physical health outcomes are consistent with previous findings that PTSD and depression symptoms differentially affect the various physical health status domains (Aversa et al, 2012), which further validates the distinction between PTSD and depression with evidence of clinical meaningfulness, and indicates the preferential interventions for individuals who may suffer more negative consequences, especially those with combined PTSD-depression symptoms. Moreover, given that LCA or LPA is a person-centered method which can identify subgroups of individuals with specific symptom presentations, some studies using LCA or LPA to examine PTSD symptom profiles have supported the need for interventions individually tailored to one's severity of symptoms and the extent of functional impairment (Hellmuth et al, 2014).…”

“…The differences in associations between specific symptom presentations of PTSD and depression with physical health outcomes (e.g. Aversa et al, 2012), serving as external validity, would not only support the distinctiveness of PTSD and depression in theory, but also suggest the preferential interventions for individuals who suffer more clinical consequences in practice.…”

Impact of childhood maltreatment on physical health-related quality of life in U.S. active duty military personnel and combat veterans

“…Additionally, our study lends further support to previously published findings that identified depression as a factor with a large effect on physical HRQoL (Aversa et al, 2012;Harder et al, 2011). In the omnibus model with childhood maltreatment, PTSD, and depression predicting physical HRQoL, only depression explained a significant proportion of the variance in HRQoL, 10% of the unique variance.…”