1998
DOI: 10.1097/00132586-199812000-00030
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Pulmonary Aspiration in Pediatric Patients During General Anesthesia

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Cited by 73 publications
(136 citation statements)
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“…(22) The risk factors reported to be associated with aspiration and regurgitation in children include greater severity of disease (ASA III-V), intravenous induction and emergency procedures. (23,24) According to Kluger et al, the mortality rate following aspiration varies between 1 in 35,000 to 1 in 72,000. (22) Other sequelae such as laryngospasm, desaturation and bronchospasm can also occur.…”
Section: Discussionmentioning
confidence: 99%
“…(22) The risk factors reported to be associated with aspiration and regurgitation in children include greater severity of disease (ASA III-V), intravenous induction and emergency procedures. (23,24) According to Kluger et al, the mortality rate following aspiration varies between 1 in 35,000 to 1 in 72,000. (22) Other sequelae such as laryngospasm, desaturation and bronchospasm can also occur.…”
Section: Discussionmentioning
confidence: 99%
“…95,127,129,173,244,261 Therefore, standard practice for fasting before elective sedation generally follows the same guidelines as for elective general anesthesia; this requirement is particularly important for solids, because aspiration of clear gastric contents causes less pulmonary injury than aspiration of particulate gastric contents. 262,263 For emergency procedures in children undergoing general anesthesia, the reported incidence of pulmonary aspiration of gastric contents from 1 institution is ∼1 in 373 compared with ∼1 in 4544 for elective anesthetics. 262 Because there are few published studies with adequate statistical power to provide guidance to the practitioner regarding the safety or risk of pulmonary aspiration of gastric contents during procedural sedation, 95, 127, 129, 173, 244, 259-261, 264-268, it is unknown whether the risk of aspiration is reduced when airway manipulation is not performed/ anticipated (eg, moderate sedation).…”
Section: Dietary Precautionsmentioning
confidence: 99%
“…268,269 Although emergency medicine studies and practice guidelines generally support a less restrictive approach to fasting for brief urgent/ emergent procedures, such as care of wounds, joint dislocation, chest tube placement, etc, in healthy children, further research in many thousands of patients would be desirable to better define the relationships between various fasting intervals and sedation complications. [262][263][264][265][266][267][268][269][270] …”
Section: Dietary Precautionsmentioning
confidence: 99%
“…In one study, almost all cases of pulmonary aspiration occurred in children who gagged or coughed during airway management, either because neuromuscular blockade was not administered or airway manipulation occurred before the child was completely paralyzed [15]. Mortality due to pulmonary aspiration is low, with an estimated incidence between zero and 1:50,000 [15,16,18].…”
Section: Asa VImentioning
confidence: 99%