Pulmonary Blastoma in an Adult: A Case with Rapid Progression

Ondo, Kaoru; Ishida, Tatsuhiro; Yamazaki, Koji; Ishii, Takeaki; Yamamoto, Kuniatsu; Odashiro, Takuya; Saito, Genkichi; Kido, Akinori; Sasaki, Yoshiichi; Yukaya, Hirofumi; Fujiwara, Megumu; Sugio, Kenji

doi:10.1080/14017439850140058

Cited by 5 publications

(2 citation statements)

References 6 publications

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“…liver, central nervous system and bones are the most frequent location of distant metastases. Rapid progression has been reported despite radical resection (17). Our patient survival is 6 months due to distant multiorgan metastasis.…”

Section: █ Discussionmentioning

confidence: 73%

Biphasic pulmonary blastoma associated with cerebral metastasis

Kılıç¹,

Yilmaz²,

Tepeoğlu³

et al. 2014

Turkish Neurosurgery

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Section: █ Discussionmentioning

confidence: 73%

Biphasic pulmonary blastoma associated with cerebral metastasis

Kılıç¹,

Yilmaz²,

Tepeoğlu³

et al. 2014

Turkish Neurosurgery

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“…PB has both a local growth pattern invading adjacent structures and a hematogenous metastatic spread. The most common symptoms www.journals.viamedica.pl that occur are cough, hemoptysis, shortness of breath, recurrent pneumonia, fever, and weight loss, but asymptomatic tumors, accounting for 40% of cases, may also be detected incidentally [22][23][24][25]. There is a similarity in the anatomical presentation of these tumors.…”

Section: Clinical and Radiographic Characteristicsmentioning

confidence: 99%

Pulmonary Blastoma: A Comprehensive Overview of A Rare Entity

Tsamis

Chachali

Gomatou

et al. 2021

Advances in Respiratory Medicine

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Introduction: Pulmonary blastoma is a rare malignancy, accounting for less than 0.5% of primary lung tumors. It belongs to the group of pulmonary sarcomatoid carcinomas, and it is typically characterized by a biphasic pattern of an epithelial and a mesenchymal component. Only a few hundred cases have been reported worldwide. The aim of this study is to review and critically assess the literature regarding pulmonary blastoma. Material and methods: A narrative literature review of PubMed database from the inception of the database up to January 2021, limited to the English language, was conducted, using combinations of the following keywords: “pulmonary blastoma”, “biphasic pulmonary blastoma”, “sarcomatoid carcinoma”. Results: Pulmonary blastoma is composed of an epithelial and a mesenchymal malignant component. Regarding pathogenesis, the origin of the biphasic cell population remains elusive. Characteristic immunohistochemical stains are supportive of diagnosis.Clinically, the symptomatology is non-specific, while 40% of the cases are asymptomatic. It is diagnosed at a younger agecompared to other types of lung cancer, and it is often non-metastatic at diagnosis allowing for surgical treatment. Data on management and survival are scarce and mainly come from isolated cases. Advances on targeted therapy may provide novel treatment options. Given the rarity of the cases, multicenter collaboration is needed in order to establish therapeutic Guideliness.

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