Pulmonary complications in cancer patients

Extracorporeal life support for support of children with malignancy and respiratory or cardiac failure: The extracorporeal life support experience*

“…However, patients may encounter complications of their malignancy or of its treatment that necessitate admission to the pediatric intensive care unit. The lungs are often affected by either the primary disease or the associated treatments leading to pneumonia, radiation pneumonitis, pneumothoraces, pulmonary edema, pulmonary leukostasis, pulmonary hemorrhage, or tumor-related pulmonary dysfunction (3)(4)(5)(6)(7)(8)(9)(10)(11). As a result, these patients may require intensive care unit admission.…”

Unsuspected Lung Pathology in Autopsies of Children with Cancer

“…acute or chronic pulmonary complications in patients with current or past cancer are well characterized in the medical literature, both in children and adults 12,[22][23][24][25][26] . these complications are diverse and include infections, fibrosis, diffuse alveolar hemorrhage; tumor infiltration, metastases, atelectasis and vascular or hemorrhagic conditions such as vascular leakage with edema and infarction, hemorrhage, pulmonary thromboembolism, etc.…”

“…these complications are diverse and include infections, fibrosis, diffuse alveolar hemorrhage; tumor infiltration, metastases, atelectasis and vascular or hemorrhagic conditions such as vascular leakage with edema and infarction, hemorrhage, pulmonary thromboembolism, etc. 10,12,16,22,27 . In contrast, their participation and magnitude in the autopsy of patients with cancer are scant and unspecific 10,11,13,16 .…”

“…In addition, autopsies allow the evaluation of diagnostic accuracy (and therefore, assessment of the quality of hospital services), help to identify differential diagnoses, unveil unsuspected conditions, and evaluate the impact of therapeutic measures [1][2][3][4][5][6][7][8] . Cancer is one of the diseases in which the autopsy yields more benefits, either for research or for the improvement of medical care [9][10][11][12] . a number of published studies have reported autopsy findings in children with cancer, but the majority of them are focused primarily on clinical-pathological inconsistencies, causes of death, omitted diagnoses, unexpected findings, or infectious complications [13][14][15] .…”

“…a number of published studies have reported autopsy findings in children with cancer, but the majority of them are focused primarily on clinical-pathological inconsistencies, causes of death, omitted diagnoses, unexpected findings, or infectious complications [13][14][15] . although the lung is one of the most frequently affected structures in patients with cancer, the medical literature concerning pulmonary involvement in pediatric patients with cancer is scarce 10,12,16 . thus, the objective of the present study was to investigate the frequency and type of lung pathology revealed by autopsies in children with cancer.…”