Pulmonary Function, Muscle Strength, and Incident Mobility Disability in Elders

Abstract

Muscle strength, including leg strength and respiratory muscle strength, are relatively independently associated with mobility disability in elders. However, the factors linking muscle strength with mobility disability are unknown. To test the hypothesis that pulmonary function mediates the association of muscle strength with the development of mobility disability in elders, we used data from a longitudinal cohort study of 844 ambulatory elders without dementia participating in the Rush Memory and Aging Project with a mean follow-up of 4.0 years (SD 5 1.39). A composite measure of pulmonary function was based on spirometric measures of forced vital capacity, forced expiratory volume, and peak expiratory flow. Respiratory muscle strength was based on maximal inspiratory pressure and expiratory pressure and leg strength based on handheld dynamometry. Mobility disability was defined as a gait speed less than or equal to 0.55 m/s based on annual assessment of timed walk. Secondary analyses considered time to loss of the ability to ambulate. In separate proportional hazards models which controlled for age, sex, and education, composite measures of pulmonary function, respiratory muscle strength, and leg strength were each associated with incident mobility disability (all P values , 0.001). Further, all three were related to the development of incident mobility disability when considered together in a single model Secondary analyses examining incident loss of the ability to ambulate revealed similar findings. Overall, these findings suggest that lower levels of pulmonary function and muscle strength are relatively independently associated with the development of mobility disability in the elderly.

Predictors of muscle strength in older individuals

“…RESULTADOS: Para mulheres, a inclusão da massa corporal ou da massa magra aumentou o R 2 CONCLUSÃO: Nossos resultados suportam a ideia de que a carga correlaciona-se com a massa corporal e massa magra, e que a carga empregada em determinado exercício está significativamente associada com a forca muscular corporal. Portanto, isso permite o desenvolvimento de um modelo preditivo de forca muscular corporal com substancial acurácia.…”

“…2,3 Resistance exercises have been recommended as a strategy to decrease the speed and magnitude of neuromuscular aging, especially as an important resource to preserve physical function and reduce the relative demand for activities of daily living, regardless of the health status. training programs.…”

Electrical Stimulation of the Abdomen Preserves Motor Performance in the Inactive Elderly: A Randomized Controlled Trial

“…Loss of muscle strength with aging has been suggested to be one of the main factors causing functional limitations in activities of daily living (ADL), such as rising from a chair or climbing up and down stairs (Guralnik et al 1995;Odding et al 1995;Schenkman et al 1996). The strength of the abdominal muscles declines easily with the process of aging and/or disuse (Chen and Kuo 1989;Buchman et al 2009), and these muscles have important roles for not only trunk function, but also the whole body motor function (Buchman et al 2008;Simões et al 2010). The subscore of the functional independence measures relating to locomotion transfers in stroke subjects at discharge was reported to be positively correlated with the trunk muscle torque values, except for isometric extension (Karatas et al 2004).…”

Exercício aeróbico ou com pesos melhora o desempenho nas atividades da vida diária de mulheres idosas

“…The muscular functional characteristics significantly decline as a result from aging 2 , especially associated with comorbidities 3 . Moreover, it has been suggested that the functional capacity to perform many activities of daily living seems to be sensibly dependent on the muscular function 4 .…”